Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes. - Wikidata - awgldk - TriplyDB

Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes.

Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes.

http://www.wikidata.org/entity/Q37247630

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3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish"Glial contributions to neurodegeneration in tauopathies.The Evolving View of Astrocytes Apolipoprotein E metabolism and functions in brain and its role in Alzheimer's disease Non-canonical soluble amyloid-beta aggregates and plaque buffering: controversies and future directions for target discovery in Alzheimer's disease.APOE gene and neuropsychiatric disorders and endophenotypes: A comprehensive review.Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network.ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease.Dynamics of the Complement, Cytokine, and Chemokine Systems in the Regulation of Synaptic Function and Dysfunction Relevant to Alzheimer's Disease.Cholesterol as a modifying agent of the neurovascular unit structure and function under physiological and pathological conditions.Astrocyte-mediated synapse remodeling in the pathological brain.Untangling Genetic Risk for Alzheimer's Disease.HIV-associated synaptic degeneration.Effect of APOE Genotype on Synaptic Proteins in Earlier Adult Life.Nature Versus Nurture: Does Proteostasis Imbalance Underlie the Genetic, Environmental, and Age-Related Risk Factors for Alzheimer's Disease?Astrocytic LRP1 Mediates Brain Aβ Clearance and Impacts Amyloid Deposition.Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.Possible positive effect of the APOE ε2 allele on cognition in early to mid-adult life.Phagocytic Roles of Glial Cells in Healthy and Diseased Brains.Phagocytic clearance of presynaptic dystrophies by reactive astrocytes in Alzheimer's disease.Neurophagy, the phagocytosis of live neurons and synapses by glia, contributes to brain development and disease.Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes.ApoE facilitates the microglial response to amyloid plaque pathology.Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion.Alzheimer's Disease, Oligomers, and Inflammation.Deciphering the Astrocyte Reaction in Alzheimer's Disease.Microglia in Alzheimer's disease Molecular Communication of a Dying Neuron in Stroke

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Novel allele-dependent role for APOE in controlling the rate of synapse pruning by astrocytes.

http://www.wikidata.org/entity/Q37247630

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 24 August 2016

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

@cs

name

Novel allele-dependent role fo ...... synapse pruning by astrocytes.

@en

Novel allele-dependent role fo ...... synapse pruning by astrocytes.

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type

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Novel allele-dependent role fo ...... synapse pruning by astrocytes.

@en

Novel allele-dependent role fo ...... synapse pruning by astrocytes.

@nl

prefLabel

Novel allele-dependent role fo ...... synapse pruning by astrocytes.

@en

Novel allele-dependent role fo ...... synapse pruning by astrocytes.

@nl

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PNAS.1609896113

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Novel allele-dependent role fo ...... synapse pruning by astrocytes.

@en

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Ben A Barres

http://www.w3.org/2001/XMLSchema#string

Chandrani Chakraborty

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Jason D Ulrich

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Julia Joung

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Philip B Verghese

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Won-Suk Chung

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P2860

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Phagocytosis of apoptotic cells in homeostasis

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

Development of a method for the purification and culture of rodent astrocytes

The classical complement cascade mediates CNS synapse elimination

Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

Isoform-specific binding of apolipoprotein E to beta-amyloid

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Alzheimer's disease is a synaptic failure

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scholarly article

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10.1073/PNAS.1609896113

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36

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David M. Holtzman

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2016-08-24T00:00:00Z

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