Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.
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Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retinaOSBP-related proteins: liganding by glycerophospholipids opens new insight into their functionTumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategiesThe effect of 7-ketocholesterol and 25-hydroxycholesterol on the integrity of the human aortic endothelial and intestinal epithelial barriersIron nanoparticles increase 7-ketocholesterol-induced cell death, inflammation, and oxidation on murine cardiac HL1-NB cells.The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells.Differential effects of the estrogen receptor agonist estradiol on toxicity induced by enzymatically-derived or autoxidation-derived oxysterols in human ARPE-19 cells.Why AMD is a disease of ageing and not of development: mechanisms and insights.7-Ketocholesterol-induced inflammation signals mostly through the TLR4 receptor both in vitro and in vivo.7-Ketocholesterol induces P-glycoprotein through PI3K/mTOR signaling in hepatoma cellsMechanisms of oxysterol-induced carcinogenesis.Novel oxysterols observed in tissues and fluids of AY9944-treated rats: a model for Smith-Lemli-Opitz syndrome.25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages.Homocysteine has anti-inflammatory properties in a hypercholesterolemic rat model in vivo7α-Hydroxycholesterol induces monocyte/macrophage cell expression of interleukin-8 via C5a receptorAnti-apoptotic phenotypes of cholestan-3β,5α,6β-triol-resistant human cholangiocytes: characteristics contributing to the genesis of cholangiocarcinoma.Oxysterols in heart failure.Oxysterols in biological systems: the gastrointestinal tract, liver, vascular wall and central nervous system.25-Hydroxycholesterol is involved in the pathogenesis of amyotrophic lateral sclerosis.Biomarkers of inflammation and oxidative stress in atherosclerosis.Advances in methods for the determination of biologically relevant lipid peroxidation products.Oxysterols and redox signaling in the pathogenesis of non-alcoholic fatty liver disease.Cholesterol Oxidation in Fish and Fish Products.Conversion of 7-dehydrocholesterol to 7-ketocholesterol is catalyzed by human cytochrome P450 7A1 and occurs by direct oxidation without an epoxide intermediate.The oxysterol 27-hydroxycholesterol increases oxidative stress and regulate Nrf2 signaling pathway in astrocyte cells.Phytochemical indicaxanthin suppresses 7-ketocholesterol-induced THP-1 cell apoptosis by preventing cytosolic Ca(2+) increase and oxidative stress.Mitochondria as a target of cardioprotection in models of preconditioning.Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatmentsHypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits.Quercetin-3-O-(2″-galloyl)-α-L-rhamnopyranoside attenuates cholesterol oxidation product-induced apoptosis by suppressing NF-κB-mediated cell death process in differentiated PC12 cells.Tyrosine kinase inhibitor AG126 reduces 7-ketocholesterol-induced cell death by suppressing mitochondria-mediated apoptotic process.Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N.Glycyrrhizin prevents 7-ketocholesterol toxicity against differentiated PC12 cells by suppressing mitochondrial membrane permeability change.The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics.Evaluation of apoptotic molecular pathways for smooth muscle cells isolated from thoracic aortic aneurysms in response to oxidized sterols.Comprehensive gene expression analyses of the rat prefrontal cortex after oxysterol treatment.Impact of 7-ketocholesterol and very long chain fatty acids on oligodendrocyte lipid membrane organization: evaluation via LAURDAN and FAMIS spectral image analysis.Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB.Olive oil polyphenols reduce oxysterols -induced redox imbalance and pro-inflammatory response in intestinal cells.
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P2860
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.
@en
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.
@nl
type
label
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.
@en
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.
@nl
prefLabel
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.
@en
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.
@nl
P2093
P2860
P1476
Side effects of oxysterols: cytotoxicity, oxidation, inflammation, and phospholipidosis.
@en
P2093
P2860
P304
P356
10.1590/S0100-879X2008000700001
P407
P577
2008-07-01T00:00:00Z