Applications of metabolomics in drug discovery and development.
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The human urine metabolomeSystems biology and biomarkers of early effects for occupational exposure limit settingSMPDB: The Small Molecule Pathway DatabaseAnalysis of bacterial biofilms using NMR-based metabolomicsDoping control using high and ultra-high resolution mass spectrometry based non-targeted metabolomics-a case study of salbutamol and budesonide abuseAdvances in Nuclear Magnetic Resonance for Drug Discovery.New tools and new biology: recent miniaturized systems for molecular and cellular biology.Identifying and quantifying metabolites by scoring peaks of GC-MS data.Comparison of peak-picking workflows for untargeted liquid chromatography/high-resolution mass spectrometry metabolomics data analysis.Biomarker Validation for Aging: Lessons from mtDNA Heteroplasmy Analyses in Early Cancer Detection.Ultra-High Mass Resolution MALDI Imaging Mass Spectrometry of Proteins and Metabolites in a Mouse Model of Glioblastoma.Metabolomic analysis and visualization engine for LC-MS data.Challenges in applying chemometrics to LC-MS-based global metabolite profile data.Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling.Metabolomics of ApcMin/+ mice genetically susceptible to intestinal cancerCharacterization of in vitro metabolic profiles of cinitapride obtained with liver microsomes of humans and various mammal species using UHPLC and chemometric methods for data analysis.Drug target inference through pathway analysis of genomics data.21st century natural product research and drug development and traditional medicinesLigand-directed profiling: applications to target drug discovery in cancer.Two dimensional NMR spectroscopic approaches for exploring plant metabolome: A reviewLeveraging metabolomics to assess the next generation of temozolomide-based therapeutic approaches for glioblastomasEffects of pre-analytical processes on blood samples used in metabolomics studies.Potential of serum metabolites for diagnosing post-stroke cognitive impairment.Chronic caloric restriction partially protects against age-related alteration in serum metabolomeLooking back through the MIST: a perspective of evolving strategies and key focus areas for metabolite safety analysis.Metabolite identification by mass spectrometry: forty years of evolution.Practical metabolomics in drug discovery.Application of in vivo metabolomics to preclinical/toxicological studies: case study on phenytoin-induced systemic toxicity.Zebrafish as a model for systems biology.Emerging applications of metabolomics in drug discovery and precision medicine.Metabolite signatures of doxorubicin induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes.The application of absolute quantitative (1)H NMR spectroscopy in drug discovery and development.Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics.Basics of mass spectrometry based metabolomics.Toxicological characterization of N-methyl-N-nitrosourea-induced cataract in rats by LC/MS-based metabonomic analysis.Mass spectrometry-based metabolomic fingerprinting for screening cold tolerance in Arabidopsis thaliana accessions.Global metabolic profiling of animal and human tissues via UPLC-MS.Discovery of Antimalarial Drugs from Streptomycetes Metabolites Using a Metabolomic Approach.Urinary hydrophilic and hydrophobic metabolic profiling based on liquid chromatography-mass spectrometry methods: Differential metabolite discovery specific to ovarian cancer.The Opportunities of Metabolomics in Drug Safety Evaluation.
P2860
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P2860
Applications of metabolomics in drug discovery and development.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Applications of metabolomics in drug discovery and development.
@en
Applications of metabolomics in drug discovery and development.
@nl
type
label
Applications of metabolomics in drug discovery and development.
@en
Applications of metabolomics in drug discovery and development.
@nl
prefLabel
Applications of metabolomics in drug discovery and development.
@en
Applications of metabolomics in drug discovery and development.
@nl
P1433
P1476
Applications of metabolomics in drug discovery and development.
@en
P304
P356
10.2165/00126839-200809050-00002
P577
2008-01-01T00:00:00Z