Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers - Wikidata - awgldk - TriplyDB

Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers

Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers

http://www.wikidata.org/entity/Q37254104

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Beta2-adaptin binds actopaxin and regulates cell spreading, migration and matrix degradation Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence [A uNick protein].Integrins and cadherins join forces to form adhesive networks.Formin-mediated actin polymerization at cell-cell junctions stabilizes E-cadherin and maintains monolayer integrity during wound repair.Cortactin: a multifunctional regulator of cellular invasiveness An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions.Extracellular signal-regulated kinase (ERK) regulates cortactin ubiquitination and degradation in lung epithelial cells Regulation of adherens junction dynamics by phosphorylation switches.Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells.Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation Amplification of MPZL1/PZR promotes tumor cell migration through Src-mediated phosphorylation of cortactin in hepatocellular carcinoma.Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens.Spatial organization of adhesion: force-dependent regulation and function in tissue morphogenesis.Dendritic spine plasticity: new regulatory roles of dynamic microtubules.Cortactin in cell migration and cancer at a glance Patterns in space: coordinating adhesion and actomyosin contractility at E-cadherin junctions.Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling.Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1.Morphogenesis in Kyoto: a confluence of cell and developmental biology.InlA-mediated entry of Listeria monocytogenes into host cells Cortactin function in invadopodia.Identification of a shootin1 isoform expressed in peripheral tissues.

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Cortactin is a functional target of E-cadherin-activated Src family kinases in MCF7 epithelial monolayers

http://www.wikidata.org/entity/Q37254104

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 19 May 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Cortactin is a functional targ ...... in MCF7 epithelial monolayers

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Cortactin is a functional targ ...... in MCF7 epithelial monolayers.

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type

label

Cortactin is a functional targ ...... in MCF7 epithelial monolayers

@en

Cortactin is a functional targ ...... in MCF7 epithelial monolayers.

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prefLabel

Cortactin is a functional targ ...... in MCF7 epithelial monolayers

@en

Cortactin is a functional targ ...... in MCF7 epithelial monolayers.

@nl

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JBC.M109.000307

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Journal of Biological Chemistry

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Cortactin is a functional targ ...... in MCF7 epithelial monolayers

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Falak M Helwani

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Gang Ren

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Robert W McLachlan

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Scott A Weed

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Suzie Verma

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P2860

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

Cortactin signalling and dynamic actin networks

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

Cortactin branches out: roles in regulating protrusive actin dynamics

Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex

Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.

Cortactin: coupling membrane dynamics to cortical actin assembly

Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation

Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts

The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells

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18913-18922

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scholarly article

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10.1074/JBC.M109.000307

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28

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19457864

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2707247

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