Identification of Kaposi's sarcoma-associated herpesvirus LANA regions important for episome segregation, replication, and persistence.
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Kaposi's Sarcoma Herpesvirus Genome PersistenceLANA binds to multiple active viral and cellular promoters and associates with the H3K4methyltransferase hSET1 complexKaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistenceThe Kaposi Sarcoma Herpesvirus Latency-associated Nuclear Antigen DNA Binding Domain Dorsal Positive Electrostatic Patch Facilitates DNA Replication and Episome Persistence.Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGASKSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA.A short sequence immediately upstream of the internal repeat elements is critical for KSHV LANA mediated DNA replication and impacts episome persistenceIdentification of Novel Kaposi's Sarcoma-Associated Herpesvirus Orf50 Transcripts: Discovery of New RTA Isoforms with Variable Transactivation Potential.
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P2860
Identification of Kaposi's sarcoma-associated herpesvirus LANA regions important for episome segregation, replication, and persistence.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Identification of Kaposi's sar ...... replication, and persistence.
@en
Identification of Kaposi's sar ...... replication, and persistence.
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type
label
Identification of Kaposi's sar ...... replication, and persistence.
@en
Identification of Kaposi's sar ...... replication, and persistence.
@nl
prefLabel
Identification of Kaposi's sar ...... replication, and persistence.
@en
Identification of Kaposi's sar ...... replication, and persistence.
@nl
P2093
P2860
P356
P1433
P1476
Identification of Kaposi's sar ...... replication, and persistence.
@en
P2093
Erika De León Vázquez
Kenneth M Kaye
Vincent J Carey
P2860
P304
12270-12283
P356
10.1128/JVI.01243-13
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P577
2013-09-04T00:00:00Z