Cisplatin-induced hair cell death requires STAT1 and is attenuated by epigallocatechin gallate.
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Cisplatin ototoxicity and protection: clinical and experimental studiesPrevention and restoration of hearing loss associated with the use of cisplatin.An integrated view of cisplatin-induced nephrotoxicity and ototoxicityCo-administration of cisplatin and furosemide causes rapid and massive loss of cochlear hair cells in mice.Downstream targets of Lmo4 are modulated by cisplatin in the inner ear of Wistar ratsCisplatin-Associated Ototoxicity: A Review for the Health ProfessionalLoss of STAT1 protects hair cells from ototoxicity through modulation of STAT3, c-Jun, Akt, and autophagy factors.Cisplatin exposure damages resident stem cells of the mammalian inner ear.Cisplatin ototoxicity blocks sensory regeneration in the avian inner earDissection of adult mouse utricle and adenovirus-mediated supporting-cell infectionQuinoline ring derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line.(-)-Epigallocatechin-3-gallate protects against NO-induced ototoxicity through the regulation of caspase- 1, caspase-3, and NF-κB activation.NOX3 NADPH oxidase couples transient receptor potential vanilloid 1 to signal transducer and activator of transcription 1-mediated inflammation and hearing lossShort interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammationEarly investigational drugs for hearing loss.Cisplatin ototoxicity involves cytokines and STAT6 signaling network.Identification of small molecule inhibitors of cisplatin-induced hair cell death: results of a 10,000 compound screen in the zebrafish lateral line.STAT1 Activation Is Enhanced by Cisplatin and Variably Affected by EGFR Inhibition in HNSCC CellsAdenosine A1 Receptor Protects Against Cisplatin Ototoxicity by Suppressing the NOX3/STAT1 Inflammatory Pathway in the Cochlea.Computational discovery of transcription factors associated with drug response.Functional mechanotransduction is required for cisplatin-induced hair cell death in the zebrafish lateral line.Tuning the metabolism of the anticancer drug cisplatin with chemoprotective agents to improve its safety and efficacy.Pharmacotherapeutic options for treating adverse effects of Cisplatin chemotherapy.Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity.Cellular response to alkylating agent MNNG is impaired in STAT1-deficients cells.EGCG enhances the efficacy of cisplatin by downregulating hsa-miR-98-5p in NSCLC A549 cells.Non-autonomous Cellular Responses to Ototoxic Drug-Induced Stress and Death.Role of STAT1 and Oxidative Stress in Gentamicin-Induced Hair Cell Death in Organ of Corti.The effect of sodium thiosulfate on the metabolism of cis-platin in human plasma in vitro.Effects of tea drinking on auditory functions in aged subjects.Osteopontin does not mitigate cisplatin ototoxicity or nephrotoxicity in adult mice.Mechanisms of Cisplatin-Induced Ototoxicity and Otoprotection.Phase II trial of post-operative radiotherapy with concurrent cisplatin plus panitumumab in patients with high-risk, resected head and neck cancer.Neomycin damage and regeneration of hair cells in both mechanoreceptor and electroreceptor lateral line organs of the larval Siberian sturgeon (Acipenser baerii).Quinoxaline protects zebrafish lateral line hair cells from cisplatin and aminoglycosides damageThe Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss
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Cisplatin-induced hair cell death requires STAT1 and is attenuated by epigallocatechin gallate.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cisplatin-induced hair cell de ...... d by epigallocatechin gallate.
@en
Cisplatin-induced hair cell de ...... d by epigallocatechin gallate.
@nl
type
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Cisplatin-induced hair cell de ...... d by epigallocatechin gallate.
@en
Cisplatin-induced hair cell de ...... d by epigallocatechin gallate.
@nl
prefLabel
Cisplatin-induced hair cell de ...... d by epigallocatechin gallate.
@en
Cisplatin-induced hair cell de ...... d by epigallocatechin gallate.
@nl
P2093
P2860
P1476
Cisplatin-induced hair cell de ...... d by epigallocatechin gallate.
@en
P2093
Edwin W Rubel
Neil M Nathanson
Nicole C Schmitt
P2860
P304
P356
10.1523/JNEUROSCI.5842-08.2009
P407
P577
2009-03-01T00:00:00Z