Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology. - Wikidata - awgldk - TriplyDB

Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.

Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.

http://www.wikidata.org/entity/Q37256088

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The Aryl Hydrocarbon Receptor: A Key Bridging Molecule of External and Internal Chemical Signals The Project MACULA Retinal Pigment Epithelium Grading System for Histology and Optical Coherence Tomography in Age-Related Macular Degeneration Knockdown of a zebrafish aryl hydrocarbon receptor repressor (AHRRa) affects expression of genes related to photoreceptor development and hematopoiesis Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degeneration Gene ontology and KEGG enrichment analyses of genes related to age-related macular degeneration.Deletion of aryl hydrocarbon receptor AHR in mice leads to subretinal accumulation of microglia and RPE atrophy.Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration.Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways.Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8+ T cell responses.Lipofuscin redistribution and loss accompanied by cytoskeletal stress in retinal pigment epithelium of eyes with age-related macular degeneration.Retinal phagocytes in age-related macular degeneration Regulation of age-related macular degeneration-like pathology by complement factor H.A novel AhR ligand, 2AI, protects the retina from environmental stress.PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration.Crosstalk between Aryl Hydrocarbon Receptor and Glucocorticoid Receptor in Human Retinal Pigment Epithelial Cells.Comparative gene expression study and pathway analysis of the human iris- and the retinal pigment epithelium.Activated Retinal Pigment Epithelium, an Optical Coherence Tomography Biomarker for Progression in Age-Related Macular Degeneration.Choroidal γδ T cells in protection against retinal pigment epithelium and retinal injury.Repurposing an orally available drug for the treatment of geographic atrophy.Rethinking Nuclear Receptors as Potential Therapeutic Targets for Retinal Diseases.Loss of NR2E3 represses AHR by LSD1 reprogramming, is associated with poor prognosis in liver cancer.Quick-freeze/deep-etch electron microscopy visualization of the mouse posterior pole.The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy Superior cervical gangliectomy induces non-exudative age-related macular degeneration in mice.Models of retinal diseases and their applicability in drug discovery.

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Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.

http://www.wikidata.org/entity/Q37256088

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 08 October 2013

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Aryl hydrocarbon receptor defi ...... r degeneration-like pathology.

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Aryl hydrocarbon receptor defi ...... r degeneration-like pathology.

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type

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Aryl hydrocarbon receptor defi ...... r degeneration-like pathology.

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Aryl hydrocarbon receptor defi ...... r degeneration-like pathology.

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Aryl hydrocarbon receptor defi ...... r degeneration-like pathology.

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Aryl hydrocarbon receptor defi ...... r degeneration-like pathology.

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PNAS.1307574110

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Proceedings of the National Academy of Sciences of the United States of America

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Aryl hydrocarbon receptor defi ...... r degeneration-like pathology.

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Amanda Bednar

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Donald P McDonnell

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Glenn J Jaffe

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Goldis Malek

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Mary A Dwyer

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Michael E Boulton

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Peng Hu

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Peter Saloupis

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Ping Yang

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Rolf Herrmann

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P2860

The aryl hydrocarbon receptor is activated by modified low-density lipoprotein

7-ketocholesterol is an endogenous modulator for the arylhydrocarbon receptor

Connections and regulation of the human estrogen receptor

Indirubin and indigo are potent aryl hydrocarbon receptor ligands present in human urine

Reduced amplitude and delayed latency in foveal response of multifocal electroretinogram in early age related macular degeneration

NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis

The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium

Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: a model of age-related macular degeneration

TGF-beta signaling and the fibrotic response

Abundant lipid and protein components of drusen

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E4069-78

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10.1073/PNAS.1307574110

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Russell S. Thomas

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2013-10-08T00:00:00Z

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