Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain

Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain

Item
http://www.wikidata.org/entity/Q37256184
The chemical evolution of oligonucleotide therapies of clinical utility.5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo.Synthesis and Characterization of a New Bivalent Ligand Combining Caffeine and Docosahexaenoic Acid.Pharmacokinetic Profiling of Conjugated Therapeutic Oligonucleotides: A High-Throughput Method Based Upon Serial Blood Microsampling Coupled to Peptide Nucleic Acid Hybridization Assay.Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable O-Phosphocholine-N-docosahexaenoyl-l-serine siRNA Conjugate in Mouse Brain.Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs.Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat.Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo.Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates.Efficient gene silencing in brain tumors with hydrophobically modified siRNAs.Tapping the RNA world for therapeutics.Self-Delivering RNAi Targeting PD-1 Improves Tumor-Specific T Cell Functionality for Adoptive Cell Therapy of Malignant Melanoma
P2860

Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain

Item
http://www.wikidata.org/entity/Q37256184
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 August 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Docosahexaenoic Acid Conjugati ...... Administration in Mouse Brain
@en
Docosahexaenoic Acid Conjugati ...... Administration in Mouse Brain.
@nl
type
label
Docosahexaenoic Acid Conjugati ...... Administration in Mouse Brain
@en
Docosahexaenoic Acid Conjugati ...... Administration in Mouse Brain.
@nl
prefLabel
Docosahexaenoic Acid Conjugati ...... Administration in Mouse Brain
@en
Docosahexaenoic Acid Conjugati ...... Administration in Mouse Brain.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Docosahexaenoic Acid Conjugati ...... Administration in Mouse Brain
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932