Mechanical injury and cytokines cause loss of cartilage integrity and upregulate proteins associated with catabolism, immunity, inflammation, and repair
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The interleukin-17 cytokine family: critical players in host defence and inflammatory diseasesA fragment of the LG3 peptide of endorepellin is present in the urine of physically active mining workers: a potential marker of physical activityFunctional imaging in OA: role of imaging in the evaluation of tissue biomechanicsStrain-dependent oxidant release in articular cartilage originates from mitochondriaEffects of doxycycline on mesenchymal stem cell chondrogenesis and cartilage repair.The chondrogenic response to exercise in the proximal femur of normal and mdx mice.Comprehensive profiling of cartilage extracellular matrix formation and maturation using sequential extraction and label-free quantitative proteomics.Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection.Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage.Use of cartilage derived from murine induced pluripotent stem cells for osteoarthritis drug screening.TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discsEffects of short-term glucocorticoid treatment on changes in cartilage matrix degradation and chondrocyte gene expression induced by mechanical injury and inflammatory cytokines.IL-10 ameliorates TNF-α induced meniscus degeneration in mature meniscal tissue in vitro.Cytokine preconditioning of engineered cartilage provides protection against interleukin-1 insult.Changes in chondrocyte gene expression following in vitro impaction of porcine articular cartilage in an impact injury model.Transport of anti-IL-6 antigen binding fragments into cartilage and the effects of injury.Acidification changes affect the inflammasome in human nucleus pulposus cells.Dynamic mechanical compression of devitalized articular cartilage does not activate latent TGF-β.Repair Potential of Matrix-Induced Bone Marrow Aspirate Concentrate and Matrix-Induced Autologous Chondrocyte Implantation for Talar Osteochondral Repair: Patterns of Some Catabolic, Inflammatory, and Pain Mediators.Mechanosignaling in bone health, trauma and inflammation.Analysing the role of endogenous matrix molecules in the development of osteoarthritis.Interleukin-1 beta and tumor necrosis factor alpha inhibit migration activity of chondrogenic progenitor cells from non-fibrillated osteoarthritic cartilageBiochemical markers of cartilage metabolism are associated with walking biomechanics 6-months following anterior cruciate ligament reconstruction.Intra-articular dexamethasone to inhibit the development of post-traumatic osteoarthritisNew developments in the treatment of osteoarthritis - focus on biologic agents.A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift.Quantitative Mass Spectrometry To Study Inflammatory Cartilage Degradation and Resulting Interactions with the Complement System.Intraarticular Administration of Dexamethasone after Mesenchymal Stem Cells Implantation Does Not Improve Significantly the Treatment of Preestablished Full-Thickness Chondral Defect in a Rabbit Model.Inflammatory conditions partly impair the mechanically mediated activation of Smad2/3 signaling in articular cartilageCan the meniscus affect the nature of a chondrocyte?Quantitative proteomics analysis of cartilage response to mechanical injury and cytokine treatment.Physiologic facet capsule stretch can induce pain & upregulate matrix metalloproteinase-3 in the dorsal root ganglia when preceded by a physiological mechanical or nonpainful chemical exposure.Differential Interactive Effects of Cartilage Traumatization and Blood Exposure In Vitro and In Vivo.A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage
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Mechanical injury and cytokines cause loss of cartilage integrity and upregulate proteins associated with catabolism, immunity, inflammation, and repair
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 04 February 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mechanical injury and cytokine ...... nity, inflammation, and repair
@en
Mechanical injury and cytokine ...... ity, inflammation, and repair.
@nl
type
label
Mechanical injury and cytokine ...... nity, inflammation, and repair
@en
Mechanical injury and cytokine ...... ity, inflammation, and repair.
@nl
prefLabel
Mechanical injury and cytokine ...... nity, inflammation, and repair
@en
Mechanical injury and cytokine ...... ity, inflammation, and repair.
@nl
P2093
P2860
P1476
Mechanical injury and cytokine ...... nity, inflammation, and repair
@en
P2093
Alan J Grodzinsky
Anna L Stevens
Forest M White
John S Wishnok
Steven R Tannenbaum
P2860
P304
P356
10.1074/MCP.M800181-MCP200
P577
2009-02-04T00:00:00Z