A CaV1.1 Ca2+ channel splice variant with high conductance and voltage-sensitivity alters EC coupling in developing skeletal muscle.
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The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialCa(V)1.1: The atypical prototypical voltage-gated Ca²⁺ channelTracks through the genome to physiological eventsNon-Ca2+-conducting Ca2+ channels in fish skeletal muscle excitation-contraction coupling.Identification and functional characterization of malignant hyperthermia mutation T1354S in the outer pore of the Cavalpha1S-subunit.Functional and biochemical properties of ryanodine receptor type 1 channels from heterozygous R163C malignant hyperthermia-susceptible mice.Functional role of voltage gated Ca(2+) channels in heart automaticity.T Cell Receptor Mediated Calcium Entry Requires Alternatively Spliced Cav1.1 Channels.Alternative splicing: functional diversity among voltage-gated calcium channels and behavioral consequences.Restricting calcium currents is required for correct fiber type specification in skeletal muscle.The α2δ-1 subunit remodels CaV1.2 voltage sensors and allows Ca2+ influx at physiological membrane potentialsEffects of inserting fluorescent proteins into the alpha1S II-III loop: insights into excitation-contraction coupling.Linker flexibility of IVS3-S4 loops modulates voltage-dependent activation of L-type Ca2+ channels.How and why are calcium currents curtailed in the skeletal muscle voltage-gated calcium channels?Weft, warp, and weave: the intricate tapestry of calcium channels regulating T lymphocyte function.Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of Ca(V)1.1 calcium channel.The role of auxiliary subunits for the functional diversity of voltage-gated calcium channels.Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?L-type Ca2+ channels in heart and brainPhysiological and pharmacological modulation of the embryonic skeletal muscle calcium channel splice variant CaV1.1eDevelopmental control of CaV1.2 L-type calcium channel splicing by Fox proteins.Enhanced dihydropyridine receptor calcium channel activity restores muscle strength in JP45/CASQ1 double knockout mice.The Ca2+ influx through the mammalian skeletal muscle dihydropyridine receptor is irrelevant for muscle performance.Divergent biophysical properties, gating mechanisms, and possible functions of the two skeletal muscle Ca(V)1.1 calcium channel splice variantsSpecific contributions of the four voltage-sensing domains in L-type calcium channels to gating and modulation.Two distinct voltage-sensing domains control voltage sensitivity and kinetics of current activation in CaV1.1 calcium channels.Exclusion of alternative exon 33 of CaV1.2 calcium channels in heart is proarrhythmogenic.Long-Term High Altitude Hypoxia influences Pulmonary Arterial L-type Calcium Channel mediated Ca(2+) signals and Contraction in Fetal and Adult Sheep.Mechanisms Responsible for ω-Pore Currents in Cav Calcium Channel Voltage-Sensing Domains.Alternative splicing alterations of Ca2+ handling genes are associated with Ca2+ signal dysregulation in myotonic dystrophy type 1 (DM1) and type 2 (DM2) myotubes.Diversification of the muscle proteome through alternative splicing.Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5.Role of putative voltage-sensor countercharge D4 in regulating gating properties of Ca1.2 and Ca1.3 calcium channels
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A CaV1.1 Ca2+ channel splice variant with high conductance and voltage-sensitivity alters EC coupling in developing skeletal muscle.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A CaV1.1 Ca2+ channel splice v ...... in developing skeletal muscle.
@en
A CaV1.1 Ca2+ channel splice v ...... in developing skeletal muscle.
@nl
type
label
A CaV1.1 Ca2+ channel splice v ...... in developing skeletal muscle.
@en
A CaV1.1 Ca2+ channel splice v ...... in developing skeletal muscle.
@nl
prefLabel
A CaV1.1 Ca2+ channel splice v ...... in developing skeletal muscle.
@en
A CaV1.1 Ca2+ channel splice v ...... in developing skeletal muscle.
@nl
P2093
P2860
P1433
P1476
A CaV1.1 Ca2+ channel splice v ...... in developing skeletal muscle.
@en
P2093
Bernhard E Flucher
Bettina Schlick
Gerald J Obermair
Natalia Molenda
Petronel Tuluc
P2860
P356
10.1016/J.BPJ.2008.09.027
P407
P577
2009-01-01T00:00:00Z