Parkinson's disease--opportunities for novel therapeutics to reduce the problems of levodopa therapy.

Parkinson's disease--opportunities for novel therapeutics to reduce the problems of levodopa therapy.

Item
http://www.wikidata.org/entity/Q37260951
Multiple roles for nicotine in Parkinson's diseaseNicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitizationThe CB1 cannabinoid receptor agonist reduces L-DOPA-induced motor fluctuation and ERK1/2 phosphorylation in 6-OHDA-lesioned ratsFocus on α4β2* and α6β2* nAChRs for Parkinson's Disease Therapeutics.Nicotinic receptor agonists decrease L-dopa-induced dyskinesias most effectively in partially lesioned parkinsonian rats.Nicotine reduces L-DOPA-induced dyskinesias by acting at beta2* nicotinic receptors.α6β2* and α4β2* nicotinic acetylcholine receptors as drug targets for Parkinson's disease.α4β2 Nicotinic receptors play a role in the nAChR-mediated decline in L-dopa-induced dyskinesias in parkinsonian rats.Role of 5-Hydroxytryptamine 1A Receptors in 6-Hydroxydopmaine-induced Catalepsy-like Immobilization in Rats: a Therapeutic Approach for Treating Catalepsy of Parkinson's Disease.Milestones in Parkinson's disease therapeutics.Targeting nicotinic receptors for Parkinson's disease therapy.Multiple controls exerted by 5-HT2C receptors upon basal ganglia function: from physiology to pathophysiology.Behavioural impact of a double dopaminergic and serotonergic lesion in the non-human primate.The effect of chronic administration of buspirone on 6-hydroxydopamine-induced catalepsy in rats.An experimental study on intracerebroventricular transplantation of human amniotic epithelial cells in a rat model of Parkinson's disease.Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning.Differentiation of hUC-MSC into dopaminergic-like cells after transduction with hepatocyte growth factor.
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Parkinson's disease--opportunities for novel therapeutics to reduce the problems of levodopa therapy.

Item
http://www.wikidata.org/entity/Q37260951
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
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bilimsel makale
@tr
scientific article published on January 2008
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Parkinson's disease--opportuni ...... problems of levodopa therapy.
@en
Parkinson's disease--opportuni ...... problems of levodopa therapy.
@nl
type
label
Parkinson's disease--opportuni ...... problems of levodopa therapy.
@en
Parkinson's disease--opportuni ...... problems of levodopa therapy.
@nl
altLabel
Parkinson's disease — opportun ...... e problems of levodopa therapy
@en
prefLabel
Parkinson's disease--opportuni ...... problems of levodopa therapy.
@en
Parkinson's disease--opportuni ...... problems of levodopa therapy.
@nl
P1433
P1476
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P1433
P1476
Parkinson's disease--opportuni ...... problems of levodopa therapy.
@en
P2093
P304
P31
P356
10.1016/S0079-6123(08)00923-0
P478
P50
P577
P698
P921