Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator
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Delivery of drugs bound to erythrocytes: new avenues for an old intravascular carrierThe Effect of Polymeric Nanoparticles on Biocompatibility of Carrier Red Blood CellsFlow-dependent channel formation in clots by an erythrocyte-bound fibrinolytic agent.Targeting of a mutant plasminogen activator to circulating red blood cells for prophylactic fibrinolysisRed blood cell-coupled tissue plasminogen activator prevents impairment of cerebral vasodilatory responses through inhibition of c-Jun-N-terminal kinase and potentiation of p38 mitogen-activated protein kinase after cerebral photothrombosis in the nSustained thromboprophylaxis mediated by an RBC-targeted pro-urokinase zymogen activated at the site of clot formation.Delivering nanoparticles to lungs while avoiding liver and spleen through adsorption on red blood cells.The shape of things to come: importance of design in nanotechnology for drug delivery.Signaling, delivery and age as emerging issues in the benefit/risk ratio outcome of tPA For treatment of CNS ischemic disorders.RBC-coupled tPA Prevents Whereas tPA Aggravates JNK MAPK-Mediated Impairment of ATP- and Ca-Sensitive K Channel-Mediated Cerebrovasodilation After Cerebral PhotothrombosisAdvanced drug delivery systems for antithrombotic agents.Red blood cells-coupled tPA prevents impairment of cerebral vasodilatory responses and tissue injury in pediatric cerebral hypoxia/ischemia through inhibition of ERK MAPK activationErythrocyte-bound tissue plasminogen activator is neuroprotective in experimental traumatic brain injury.Drug delivery by red blood cells: vascular carriers designed by mother nature.Bio-inspired, bioengineered and biomimetic drug delivery carriers.Vascular targeting of antithrombotic agents.Drug delivery by red blood cells.Coagulopathy after traumatic brain injury.Approaches to erythrocyte-mediated drug delivery.Erythrocytes-based synthetic delivery systems: transition from conventional to novel engineering strategies.Engineering of plasminogen activators for targeting to thrombus and heightening thrombolytic efficacy.Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems.Erythrocytes as Carriers for Drug Delivery in Blood Transfusion and Beyond.Drug delivery by erythrocytes: "Primum non nocere".No-reflow phenomenon and endothelial glycocalyx of microcirculation.The spatial dynamics of fibrin clot dissolution catalyzed by erythrocyte-bound vs. free fibrinolytics.Cardiological biopharmaceuticals in the conception of drug targeting delivery: practical results and research perspectives.Soluble urokinase receptor conjugated to carrier red blood cells binds latent pro-urokinase and alters its functional profile.Antioxidant enzymes as potential targets in cardioprotection and treatment of cardiovascular diseases. Enzyme antioxidants: the next stage of pharmacological counterwork to the oxidative stress.Cell-Based Drug Delivery and Use of Nano-and Microcarriers for Cell Functionalization.Recent advances in targeted delivery of tissue plasminogen activator for enhanced thrombolysis in ischaemic stroke.Nanoparticle Properties Modulate Their Attachment and Effect on Carrier Red Blood Cells.
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Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 September 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cerebrovascular thromboprophyl ...... sue-type plasminogen activator
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Cerebrovascular thromboprophyl ...... ue-type plasminogen activator.
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type
label
Cerebrovascular thromboprophyl ...... sue-type plasminogen activator
@en
Cerebrovascular thromboprophyl ...... ue-type plasminogen activator.
@nl
prefLabel
Cerebrovascular thromboprophyl ...... sue-type plasminogen activator
@en
Cerebrovascular thromboprophyl ...... ue-type plasminogen activator.
@nl
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Cerebrovascular thromboprophyl ...... sue-type plasminogen activator
@en
P2093
Bi-Sen Ding
Dmitriy Atochin
Douglas B Cines
Juan-Carlos Murciano
Kristina Danielyan
Kumkum Ganguly
Paul L Huang
Scott E Kasner
Sergei Zaitsev
Vladimir R Muzykantov
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P304
P356
10.1161/CIRCULATIONAHA.107.750257
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P577
2008-09-15T00:00:00Z