Cortagine, a CRF1 agonist, induces stresslike alterations of colonic function and visceral hypersensitivity in rodents primarily through peripheral pathways.
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Activation of corticotropin-releasing factor receptor 2 mediates the colonic motor coping response to acute stress in rodentsChanges in Enteric Neurons of Small Intestine in a Rat Model of Irritable Bowel Syndrome with Diarrhea.Role of Corticotropin-releasing Factor in Gastrointestinal Permeability.Stress and visceral pain: from animal models to clinical therapiesEnhanced cytokine-induced mechanical hyperalgesia in skeletal muscle produced by a novel mechanism in rats exposed to unpredictable sound stress.Corticotropin releasing factor in the rat colon: expression, localization and upregulation by endotoxinIrritable bowel syndrome: a clinical reviewPsychological Stress Induces Visceral Analgesic or Hyperalgesic Response in Rodents: A Role of Preconditions.Role of Corticotropin-releasing Factor Signaling in Stress-related Alterations of Colonic Motility and Hyperalgesia.The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats.Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities.Stress-related alterations of visceral sensation: animal models for irritable bowel syndrome study.Corticotropin-releasing factor signaling and visceral response to stress.Selective agonists of somatostatin receptor subtype 1 or 2 injected peripherally induce antihyperalgesic effect in two models of visceral hypersensitivity in miceActivation of Type 1 CRH receptor isoforms induces serotonin release from human carcinoid BON-1N cells: an enterochromaffin cell model.Stress-induced visceral analgesia assessed non-invasively in rats is enhanced by prebiotic diet.Corticotropin releasing factor signaling in colon and ileum: regulation by stress and pathophysiological implicationsA role for corticotropin-releasing factor in functional gastrointestinal disorders.Repeated psychological stress-induced alterations of visceral sensitivity and colonic motor functions in mice: influence of surgery and postoperative single housing on visceromotor responsesThe joint power of sex and stress to modulate brain-gut-microbiota axis and intestinal barrier homeostasis: implications for irritable bowel syndrome.Stress and the Microbiota-Gut-Brain Axis in Visceral Pain: Relevance to Irritable Bowel Syndrome.IBS and IBD - separate entities or on a spectrum?Visceral analgesia induced by acute and repeated water avoidance stress in rats: sex difference in opioid involvement.Endogenous CRF in rat large intestine mediates motor and secretory responses to stress.Corticosterone mediates stress-related increased intestinal permeability in a region-specific manner.Stress management affects outcomes in the pathophysiology of an endometriosis modelExpression of corticotropin releasing factor receptor type 1 (CRF1) in the human gastrointestinal tract and upregulation in the colonic mucosa in patients with ulcerative colitis.PKCγ receptor mediates visceral nociception and hyperalgesia following exposure to PTSD-like stress in the spinal cord of rats.Repeated Water Avoidance Stress Alters Mucosal Mast Cell Counts, Interleukin-1β Levels with Sex Differences in the Distal Colon of Wistar Rats.Sex hormones in the modulation of irritable bowel syndrome.Repeated otilonium bromide administration prevents neurotransmitter changes in colon of rats underwent to wrap restraint stress.Maternal separation as a model of brain-gut axis dysfunction.Corticotropin-releasing factor receptor type 1 and type 2 interaction in irritable bowel syndrome.Physiology of Visceral Pain.P2X3 receptor-mediated visceral hyperalgesia and neuronal sensitization following exposure to PTSD-like stress in the dorsal root ganglia of rats.Epithelial expression and function of trypsin-3 in irritable bowel syndrome.Characterization of Multisubstituted Corticotropin Releasing Factor (CRF) Peptide Antagonists (Astressins).Corticotropin-releasing Factor Changes the Phenotype and Function of Dendritic Cells in Mouse Mesenteric Lymph Nodes.Multi-center randomized controlled trial of cognitive treatment, placebo, oxybutynin, bladder training, and pelvic floor training in children with functional urinary incontinence.Novel insights in the role of peripheral corticotropin-releasing factor and mast cells in stress-induced visceral hypersensitivity.
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Cortagine, a CRF1 agonist, induces stresslike alterations of colonic function and visceral hypersensitivity in rodents primarily through peripheral pathways.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 30 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cortagine, a CRF1 agonist, ind ...... y through peripheral pathways.
@en
Cortagine, a CRF1 agonist, ind ...... y through peripheral pathways.
@nl
type
label
Cortagine, a CRF1 agonist, ind ...... y through peripheral pathways.
@en
Cortagine, a CRF1 agonist, ind ...... y through peripheral pathways.
@nl
prefLabel
Cortagine, a CRF1 agonist, ind ...... y through peripheral pathways.
@en
Cortagine, a CRF1 agonist, ind ...... y through peripheral pathways.
@nl
P2093
P2860
P50
P356
P1476
Cortagine, a CRF1 agonist, ind ...... y through peripheral pathways.
@en
P2093
David W Adelson
Jean Rivier
Karina Pambukchian
Lixin Wang
Stefan Brunnhuber
P2860
P304
P356
10.1152/AJPGI.00072.2009
P577
2009-04-30T00:00:00Z