Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.

Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.

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http://www.wikidata.org/entity/Q37266999
The hepatic cannabinoid 1 receptor as a modulator of hepatic energy state and food intakeTamoxifen Isomers and Metabolites Exhibit Distinct Affinity and Activity at Cannabinoid Receptors: Potential Scaffold for Drug DevelopmentHepatic cannabinoid receptor type 1 mediates alcohol-induced regulation of bile acid enzyme genes expression via CREBH.The Orphan Nuclear Receptor ERRγ Regulates Hepatic CB1 Receptor-Mediated Fibroblast Growth Factor 21 Gene Expression.RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure.Transcriptional cross talk between orphan nuclear receptor ERRγ and transmembrane transcription factor ATF6α coordinates endoplasmic reticulum stress response.Inverse agonist of nuclear receptor ERRγ mediates antidiabetic effect through inhibition of hepatic gluconeogenesis.Dissecting the role of CB1 receptors on chronic liver diseasesRegulation of the transcriptome by ER stress: non-canonical mechanisms and physiological consequences.Orphan nuclear receptor Errγ induces C-reactive protein gene expression through induction of ER-bound Bzip transmembrane transcription factor CREBH.Orphan nuclear receptor oestrogen-related receptor γ (ERRγ) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression.Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells.Orphan nuclear receptor ERRγ is a key regulator of human fibrinogen gene expression.22-S-Hydroxycholesterol protects against ethanol-induced liver injury by blocking the auto/paracrine activation of MCP-1 mediated by LXRα.In vitro metabolism of an estrogen-related receptor γ modulator, GSK5182, by human liver microsomes and recombinant cytochrome P450s.Inverse agonist of estrogen-related receptor γ controls Salmonella typhimurium infection by modulating host iron homeostasis.PKB/Akt phosphorylation of ERRγ contributes to insulin-mediated inhibition of hepatic gluconeogenesis.
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Estrogen-related receptor γ controls hepatic CB1 receptor-mediated CYP2E1 expression and oxidative liver injury by alcohol.

Item
http://www.wikidata.org/entity/Q37266999
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 29 September 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Estrogen-related receptor γ co ...... ative liver injury by alcohol.
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Estrogen-related receptor γ co ...... ative liver injury by alcohol.
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type
label
Estrogen-related receptor γ co ...... ative liver injury by alcohol.
@en
Estrogen-related receptor γ co ...... ative liver injury by alcohol.
@nl
prefLabel
Estrogen-related receptor γ co ...... ative liver injury by alcohol.
@en
Estrogen-related receptor γ co ...... ative liver injury by alcohol.
@nl
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Estrogen-related receptor γ co ...... dative liver injury by alcohol
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10.1136/GUTJNL-2012-303347
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P433
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P5875
P698
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