Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.
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A perspective on dietary phytochemicals and cancer chemoprevention: oxidative stress, nrf2, and epigenomicsTrials with 'epigenetic' drugs: an updateQuality control and statistical modeling for environmental epigenetics: a study on in utero lead exposure and DNA methylation at birthProperly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity."Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence.Understanding gene regulatory mechanisms by integrating ChIP-seq and RNA-seq data: statistical solutions to biological problems.CXCR1/2 pathways in paclitaxel-induced neuropathic painHSPC117 is regulated by epigenetic modification and is involved in the migration of JEG-3 cellsC5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development.Computational methods for de novo protein design and its applications to the human immunodeficiency virus 1, purine nucleoside phosphorylase, ubiquitin specific protease 7, and histone demethylases.Chemical and biochemical approaches in the study of histone methylation and demethylationEpigenetics of prostate cancer and the prospect of identification of novel drug targets by RNAi screening of epigenetic enzymes.Epigenetic Signatures in Breast Cancer: Clinical PerspectiveSmall-molecule blocks malignant astrocyte proliferation and induces neuronal gene expressionCancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation.Epigenetic drugs against cancer: an evolving landscape.Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.Determination of chidamide in rat plasma by LC-MS and its application to pharmacokinetics study.HDAC-inhibitor (S)-8 disrupts HDAC6-PP1 complex prompting A375 melanoma cell growth arrest and apoptosis.Interpreting clinical assays for histone deacetylase inhibitors.Epigenomics and ovarian carcinoma.Histone deacetylase inhibitors: clinical implications for hematological malignancies.DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activityARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias.Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.Butyrate histone deacetylase inhibitors.Current evidence for histone deacetylase inhibitors in pancreatic cancer.Histone deacetylase inhibitors and pancreatic cancer: are there any promising clinical trials?Overview of major classes of plant-derived anticancer drugsHistone acetyltransferase inhibitors and preclinical studies.Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells.The application of delivery systems for DNA methyltransferase inhibitors.Small-molecule chromatin-modifying agents: therapeutic applications.Targeting epigenetic networks with polypharmacology: a new avenue to tackle cancer.Epigenetic-based therapies in cancer: progress to date.The pituitary tumour epigenome: aberrations and prospects for targeted therapy.DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies.Cancers with wrong HATs: the impact of acetylation.Curcumin as a regulator of epigenetic events.Epigenetics in the development, modification, and prevention of cardiovascular disease.
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P2860
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 22 August 2008
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.
@en
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.
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type
label
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.
@en
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.
@nl
prefLabel
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.
@en
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.
@nl
P1476
Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.
@en
P304
P356
10.1016/J.BIOCEL.2008.08.020
P577
2008-08-22T00:00:00Z