Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils
about
Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malariaPhosphoinositide-mediated oligomerization of a defensin induces cell lysisPlasmodium falciparum merozoite surface protein 3: oligomerization, self-assembly, and heme complex formationConformational dynamics and antigenicity in the disordered malaria antigen merozoite surface protein 2A phase 1 trial of MSP2-C1, a blood-stage malaria vaccine containing 2 isoforms of MSP2 formulated with Montanide® ISA 720In-silico screening, identification and validation of a novel vaccine candidate in the fight against Plasmodium falciparumP-selectin is a host receptor for Plasmodium MSP7 ligandsInsights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions.Identification of key residues involved in fibril formation by the conserved N-terminal region of Plasmodium falciparum merozoite surface protein 2 (MSP2)High affinity antibodies to Plasmodium falciparum merozoite antigens are associated with protection from malaria.Expanding the proteome: disordered and alternatively folded proteins.Structural insights into functional and pathological amyloid.Plasmodium falciparum merozoite surface protein 2: epitope mapping and fine specificity of human antibody response against non-polymorphic domains.EGCG disaggregates amyloid-like fibrils formed by Plasmodium falciparum merozoite surface protein 2Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate.Solution conformation, backbone dynamics and lipid interactions of the intrinsically unstructured malaria surface protein MSP2.Differences in affinity of monoclonal and naturally acquired polyclonal antibodies against Plasmodium falciparum merozoite antigens.A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein InteractionsIn silico Identification and Validation of a Linear and Naturally Immunogenic B-Cell Epitope of the Plasmodium vivax Malaria Vaccine Candidate Merozoite Surface Protein-9Antigenic characterization of an intrinsically unstructured protein, Plasmodium falciparum merozoite surface protein 2.Strain-transcending immune response generated by chimeras of the malaria vaccine candidate merozoite surface protein 2.Acquired antibodies to merozoite antigens in children from Uganda with uncomplicated or severe Plasmodium falciparum malaria.Redefining an epitope of a malaria vaccine candidate, with antibodies against the N-terminal MSA-2 antigen of Plasmodium harboring non-natural peptide bondsBinding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.Possible roles of amyloids in malaria pathophysiologyA novel malaria vaccine candidate antigen expressed in Tetrahymena thermophila.Sequential processing of merozoite surface proteins during and after erythrocyte invasion by Plasmodium falciparum.A novel structural effector from rust fungi is capable of fibril formation.Effects of environmental factors on MSP21-25 aggregation indicate the roles of hydrophobic and electrostatic interactions in the aggregation process.The Physiological and Pathological Implications of the Formation of Hydrogels, with a Specific Focus on Amyloid Polypeptides.Functional amyloid: widespread in Nature, diverse in purpose.
P2860
Q26772878-6284108E-39E5-4879-93A4-CBA45D6DA2C5Q27682739-D3D208B7-5EED-4622-A60D-1722DD5223BCQ27974527-5504A61A-3B90-4F7C-918B-4FC031B9AFDAQ28543881-C40AEF12-B50A-4A40-86A7-0953BB431AE2Q28744696-51A77929-45CB-42AA-8F99-FD2FA6B396D3Q30041123-0C10D0A2-CEC7-47FB-B11F-D87125B59B00Q30043222-42F0FFB9-4738-42E6-A97A-70CCAEFD2FA6Q30380793-FF9BD9A2-B2C6-4092-B8B2-4DCB71EEA9F5Q34168560-58EBD70B-565E-4E6D-87FC-B565DD18CCA9Q34171724-8FDD22BC-62FB-4E2F-A8BD-85FBF62C3A06Q34197530-F9A68485-36A4-4E3B-93BF-F38F8D2B4F61Q34947293-4D047962-5A28-4045-B48B-B1A6E98FD3BEQ35060442-D433C2DC-6A78-4375-A236-1BD9F64519CAQ35169135-CC98E1BE-BE1B-4CBB-B685-AA705E63282BQ35595561-08933299-8091-4735-A785-9E4373EA3A16Q35607939-7057ABA8-6689-48AD-9756-1D8F7792EA1CQ35684692-B0769540-B719-4AAC-92F7-94A408ACDDF1Q35877857-D2306E73-F1BC-4E28-934B-6D1E3C76B42FQ35898819-0F379D7B-BCB0-48D8-BA36-5399086BA1C0Q36396844-50F48BEF-5EB7-47B0-9208-9C7B7601842AQ36569534-7B6E764A-B7C2-4A3F-B625-D18B3CE912AEQ37124766-F3845563-19E9-4089-8E57-773ADDF6E642Q37180346-F9C447C8-37E1-4989-8C84-4A3D8D2B88C3Q37323050-614AE689-4AD3-43E7-9162-FAB593D19820Q37474223-97386AD5-7635-4184-8E96-11F194C226A2Q37529646-00777063-F86A-440B-9A14-89BDDCEBF0E4Q37643916-05F0A9AA-2BAB-4EC0-8DAC-BE6EC31D86BEQ44866603-13A956D7-3A9D-40DB-960A-74341B015AF0Q46280490-CF5FB156-5AA0-4F21-AE14-CBC3F632C7B8Q46302852-91787DEB-4116-46AB-9721-02B6872EDF8FQ50786315-8AB90ECA-BAD8-4275-9C25-1581910D91AC
P2860
Plasmodium falciparum merozoite surface protein 2 is unstructured and forms amyloid-like fibrils
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Plasmodium falciparum merozoit ...... and forms amyloid-like fibrils
@en
Plasmodium falciparum merozoit ...... nd forms amyloid-like fibrils.
@nl
type
label
Plasmodium falciparum merozoit ...... and forms amyloid-like fibrils
@en
Plasmodium falciparum merozoit ...... nd forms amyloid-like fibrils.
@nl
prefLabel
Plasmodium falciparum merozoit ...... and forms amyloid-like fibrils
@en
Plasmodium falciparum merozoit ...... nd forms amyloid-like fibrils.
@nl
P2093
P2860
P50
P1476
Plasmodium falciparum merozoit ...... and forms amyloid-like fibrils
@en
P2093
Anthony N Hodder
Geoffrey J Howlett
Gert H Talbo
Jesse Schloegel
Kleo Vingas
Lynne J Waddington
Vince J Murphy
P2860
P304
P356
10.1016/J.MOLBIOPARA.2009.03.012
P50
P577
2009-04-09T00:00:00Z