Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis. - Wikidata - awgldk - TriplyDB

Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.

Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.

http://www.wikidata.org/entity/Q37273233

about

HIV therapeutic vaccines: moving towards a functional cure HIV Replication Is Not Controlled by CD8+ T Cells during the Acute Phase of the Infection in Humanized Mice A DNA vaccine encoding multiple HIV CD4 epitopes elicits vigorous polyfunctional, long-lived CD4+ and CD8+ T cell responses Immune responses during spontaneous control of HIV and AIDS: what is the hope for a cure?The cytokine network of acute HIV infection: a promising target for vaccines and therapy to reduce viral set-point?Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous Simian Immunodeficiency Virus-specific CD8(+) T cell clones during acute and chronic infection of rhesus macaques In vivo CD8+ T-cell suppression of siv viremia is not mediated by CTL clearance of productively infected cells.Experimental depletion of CD8+ cells in acutely SIVagm-infected African Green Monkeys results in increased viral replication.Transduction of SIV-specific TCR genes into rhesus macaque CD8+ T cells conveys the ability to suppress SIV replication.Diminished viral control during simian immunodeficiency virus infection is associated with aberrant PD-1hi CD4 T cell enrichment in the lymphoid follicles of the rectal mucosa.Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates Immune clearance of highly pathogenic SIV infection.TCR triggering transcriptionally downregulates CCR5 expression on rhesus macaque CD4(+) T-cells with no measurable effect on susceptibility to SIV infection CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.Induction of immunity to human immunodeficiency virus type-1 by vaccination.Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL.Vaccination with live attenuated simian immunodeficiency virus causes dynamic changes in intestinal CD4+CCR5+ T cells.B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers IL-15 delays suppression and fails to promote immune reconstitution in virally suppressed chronically SIV-infected macaques.Specific pathogen-free status alters immunophenotype in rhesus macaques: implications for the study of simian immunodeficiency virus.Long-term control of simian immunodeficiency virus (SIV) in cynomolgus macaques not associated with efficient SIV-specific CD8+ T-cell responses.Genital tract inflammation during early HIV-1 infection predicts higher plasma viral load set point in women.Simian Immunodeficiency Virus SIVsab Infection of Rhesus Macaques as a Model of Complete Immunological Suppression with Persistent Reservoirs of Replication-Competent Virus: Implications for Cure Research.CD8+ lymphocyte depletion without SIV infection does not produce metabolic changes or pathological abnormalities in the rhesus macaque brain.Naive T cells are dispensable for memory CD4+ T cell homeostasis in progressive simian immunodeficiency virus infection.Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques.Lessons in nonhuman primate models for AIDS vaccine research: from minefields to milestones.Effect of IL-7 Therapy on Naive and Memory T Cell Homeostasis in Aged Rhesus Macaques Harnessing CD4⁺ T cell responses in HIV vaccine development.Limited dissemination of pathogenic SIV after vaginal challenge of rhesus monkeys immunized with a live, attenuated lentivirus Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates Resistance to infection, early and persistent suppression of simian immunodeficiency virus SIVmac251 viremia, and significant reduction of tissue viral burden after mucosal vaccination in female rhesus macaques CD8+ T cell control of HIV--a known unknown.Rare Control of SIVmac239 Infection in a Vaccinated Rhesus Macaque.CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.The well-tempered SIV infection: Pathogenesis of SIV infection in natural hosts in the wild, with emphasis on virus transmission and early events post-infection that may contribute to protection from disease progression.Dual mechanism of impairment of interleukin-7 (IL-7) responses in human immunodeficiency virus infection: decreased IL-7 binding and abnormal activation of the JAK/STAT5 pathway.Insights into the Impact of CD8+ Immune Modulation on Human Immunodeficiency Virus Evolutionary Dynamics in Distinct Anatomical Compartments by Using Simian Immunodeficiency Virus-Infected Macaque Models of AIDS Progression.CD8+ cell depletion of SHIV89.6P-infected macaques induces CD4+ T cell proliferation that contributes to increased viral loads.Propionibacterium acnes Enhances the Immunogenicity of HIVBr18 Human Immunodeficiency Virus-1 Vaccine.

P2860

Q27002180-46F3B42E-91DA-40AF-8A70-398592673826 Q28607258-25B6F36C-CBF1-4A06-A11C-6678AE9E598D Q28742853-4679BA5E-550A-4D89-AED1-F9A8791DC0EB Q30362489-BBCC7B16-4603-4BA3-A5D7-A22640701948 Q30406147-B9EE13BE-D2F2-4CA2-B8A4-A8D5A54C2B7D Q33554963-EC18C697-9BFB-4BDF-A975-FBEA4682C593 Q33618013-07162401-6D44-4BAD-8046-8DE2FF14C9BC Q33888012-DB89AFFC-3219-4E1E-9FD8-EE13D562CA1A Q34008900-91698FFC-392F-4DD7-81DD-B23704FF2AD2 Q34364695-3CE017CF-2E5F-4BAA-831B-7B53C556E410 Q34369832-BD09F140-8369-4BA6-84BE-1DF9E344BC50 Q34370314-BF2FA26D-9015-41B1-8F5A-70CEB70E5BF6 Q34404437-3AA705D7-0508-4C51-B155-CA17E830AA76 Q34433569-75EE6A91-83BB-4104-8B6A-8AF65E1F7941 Q34540645-C477E3C5-DB4F-4E31-82FD-B3FF76D2000A Q34550802-492AC9B3-BCB1-4D16-9397-BEFD338DBFAD Q34573745-3DD848E5-3E47-4DCB-AF1A-2DA158EDA02C Q35058635-71AF0E51-0196-45BD-9F3D-64281CE4BB87 Q35197395-8B17A237-3160-40FD-A511-AD432978CCC9 Q35267854-A7C99F31-6194-4399-BDDE-959DE3932D4E Q35487807-67F3815B-320A-42F7-822C-C80FF603D099 Q35628640-E6A298F1-9453-47C4-9195-0329A3319A13 Q35641175-D89D09E6-CB3D-437F-9251-B0BAE8EF293F Q35738499-54D3C877-291D-4772-BC66-9FCC3D694EBE Q35894221-07C83F91-4D91-456D-B98C-B5C3E93E689D Q35913945-9755FAA4-34FD-4DB0-A85F-E1E067A4614E Q36009232-A5950D3A-3EBB-4297-9D81-97DE0B01B375 Q36197021-EC8D1385-278C-49A3-BB85-A8645356D187 Q36766715-5EF9C80B-1F92-47D8-AB0B-5BE9E633D120 Q37368482-B3306278-645E-4515-B2AF-E3657E3C6136 Q37409258-1BE14909-616D-479C-9C32-0E50DAD1FD04 Q37547763-43DB795A-A230-4FBA-AEA6-7A4307F6DD2D Q37686094-FA473356-D1BA-4D76-BE8B-D71E6C18B0D2 Q38786450-BDF75DF6-C74D-4574-9BB6-D02849DCA459 Q40532397-CAA57B0D-78E5-4055-B626-131739EFD9D1 Q40619853-C80D40A5-982F-47F0-9C23-5773B8550C92 Q41859080-7FA0AD6C-08A9-46D0-978F-4555203D0F16 Q41933419-47D3D266-5315-4A21-A77A-C14D6A210C86 Q42577154-719B657F-62E9-4A1E-937F-5361A556343A Q50281273-D636F2DA-E51B-4FE1-B904-4429ED79658A

P2860

Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.

http://www.wikidata.org/entity/Q37273233

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 22 June 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Profound CD4+/CCR5+ T cell exp ...... accelerated SIV pathogenesis.

@en

Profound CD4+/CCR5+ T cell exp ...... accelerated SIV pathogenesis.

@nl

type

label

Profound CD4+/CCR5+ T cell exp ...... accelerated SIV pathogenesis.

@en

Profound CD4+/CCR5+ T cell exp ...... accelerated SIV pathogenesis.

@nl

prefLabel

Profound CD4+/CCR5+ T cell exp ...... accelerated SIV pathogenesis.

@en

Profound CD4+/CCR5+ T cell exp ...... accelerated SIV pathogenesis.

@nl

P1433

Q37273233-5DA6C4AF-9F66-4B73-9755-DE732AB52EF3

P1476

Q37273233-0AE0D7D2-B77C-4343-86D2-74188EB41068

P2093

Q37273233-0B5A5A13-B6E1-43CF-AFCA-DE612859AEAD

Q37273233-2CEA094B-A625-4E4B-A548-1B03858D194D

Q37273233-336B2420-0AA1-41E4-8523-97025D906062

Q37273233-492A63C0-9FBA-475D-A0B2-09D51F4B2008

Q37273233-4D621A78-69BC-4034-8CD4-D630DD3A2342

Q37273233-4EE1933B-B178-440B-A62C-149EDC53383A

Q37273233-64E30DA6-4E14-41EF-A8B8-2296577105CD

Q37273233-78F727C9-683C-4FDE-A6F5-67DF86DADC87

Q37273233-7A3B1919-31EE-4CE1-8F25-A293B275D173

Q37273233-8EA22FE1-4902-4A03-98E8-6D63B3B8665E

P2860

Q37273233-033EE986-4390-4F75-A1B0-E25C2FB67AED

Q37273233-037B07B4-893A-420B-8EDF-9B8F9F433F33

Q37273233-11CC2DBB-C4CB-4EE0-92A4-48E764B25942

Q37273233-1725E662-A31F-43A3-8D58-8E378C7848E4

Q37273233-21EBD789-E46F-40ED-ACA0-547E43695B5B

Q37273233-22863F9A-DD92-4929-972A-83556073CA19

Q37273233-2D769F91-A62A-4FA8-A876-07726C8A093B

Q37273233-2EEB62F9-7EA1-4AC3-A61E-6F02DD47DC1C

Q37273233-3708798B-9951-4CF2-AB9E-37DB826304B3

Q37273233-38AA5060-0E73-4483-9691-8840D606959B

P304

Q37273233-DB4195CE-78D7-47F0-BBB4-A7B72756E92C

P31

Q37273233-2183EB5E-3D5B-4797-96BE-26D39337B1BE

P356

Q37273233-70D58B6B-C95D-4467-87F4-B58271FE83EF

P407

Q37273233-1BCAAA87-B385-4130-8460-5B9EBB2873DA

P433

Q37273233-86D9971F-D8F9-4D2B-AD00-8F39D6CA9D4C

P478

Q37273233-EED0392D-958A-4ECE-B9DE-4EDEAB5E2F2A

P50

Q37273233-1D9C2A4D-E49F-4D34-B460-1D53359A57C9

Q37273233-225CD9F3-01F9-482A-A4D5-48B3BCA122D9

P577

Q37273233-A0B3CED3-A9C5-4651-9AD5-DE8446D33740

P5875

Q37273233-97308749-B4D1-4666-A3C0-DA95E2B96BD6

P698

Q37273233-D7AE6788-541D-4C66-9606-6BC8B785C16D

P921

Q37273233-85BE2CF2-B2D0-4C5B-BFF7-670D366993FE

Q37273233-C878F1A8-77C3-42C2-BB18-E673C8763BFD

P932

Q37273233-70BC329F-5D05-4D79-875E-9E009A2F800F

P356

P1433

Journal of Experimental Medicine

P1476

Profound CD4+/CCR5+ T cell exp ...... r accelerated SIV pathogenesis

@en

P2093

Afam Okoye

http://www.w3.org/2001/XMLSchema#string

Alfred W Legasse

http://www.w3.org/2001/XMLSchema#string

Andrew W Sylwester

http://www.w3.org/2001/XMLSchema#string

Donald L Sodora

http://www.w3.org/2001/XMLSchema#string

Francois Villinger

http://www.w3.org/2001/XMLSchema#string

Haesun Park

http://www.w3.org/2001/XMLSchema#string

Jeffrey D Lifson

http://www.w3.org/2001/XMLSchema#string

Lia Coyne-Johnson

http://www.w3.org/2001/XMLSchema#string

Louis J Picker

http://www.w3.org/2001/XMLSchema#string

Michael K Axthelm

http://www.w3.org/2001/XMLSchema#string

P2860

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): Implications for HIV-1 infections of humans

Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques

Intrinsic susceptibility of rhesus macaque peripheral CD4(+) T cells to simian immunodeficiency virus in vitro is predictive of in vivo viral replication

P304

1575-1588

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.20090356

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

206

http://www.w3.org/2001/XMLSchema#string

P50

Joshua M. Walker

Joern E Schmitz

P577

2009-06-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26310821

http://www.w3.org/2001/XMLSchema#string

P698

19546246

http://www.w3.org/2001/XMLSchema#string

P921

P932

2715089

http://www.w3.org/2001/XMLSchema#string