ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion.
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The Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine OxidationsExcision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylationDynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes.Methylation-independent DNA binding modulates specificity of Repressor of Silencing 1 (ROS1) and facilitates demethylation in long substrates.Recent advances in the structural mechanisms of DNA glycosylasesAP endonucleases process 5-methylcytosine excision intermediates during active DNA demethylation in Arabidopsis.Domain structure of the DEMETER 5-methylcytosine DNA glycosylase.The study of a barley epigenetic regulator, HvDME, in seed development and under drought.The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activityAn AP endonuclease functions in active DNA demethylation and gene imprinting in Arabidopsis [corrected].A DNA 3' phosphatase functions in active DNA demethylation in Arabidopsis.Sequencing of DNA Lesions Facilitated by Site-Specific Excision via Base Excision Repair DNA Glycosylases Yielding Ligatable Gaps.Early steps of active DNA demethylation initiated by ROS1 glycosylase require three putative helix-invading residues.DDM1 and ROS1 have a role in UV-B induced- and oxidative DNA damage in A. thaliana.Excision of 5-hydroxymethylcytosine by DEMETER family DNA glycosylases.5-methylcytosine recognition by Arabidopsis thaliana DNA glycosylases DEMETER and DML3Protecting DNA from errors and damage: an overview of DNA repair mechanisms in plants compared to mammals.Role of Base Excision "Repair" Enzymes in Erasing Epigenetic Marks from DNADNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications.The genome-wide identification and transcriptional levels of DNA methyltransferases and demethylases in globe artichoke.Demethylation initiated by ROS1 glycosylase involves random sliding along DNA.The DNA repair protein XRCC1 functions in the plant DNA demethylation pathway by stimulating cytosine methylation (5-meC) excision, gap tailoring, and DNA ligation.A discontinuous DNA glycosylase domain in a family of enzymes that excise 5-methylcytosine.AtROS1 overexpression provides evidence for epigenetic regulation of genes encoding enzymes of flavonoid biosynthesis and antioxidant pathways during salt stress in transgenic tobacco.Dual control of ROS1-mediated active DNA demethylation by DNA damage-binding protein 2 (DDB2).
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ROS1 5-methylcytosine DNA glycosylase is a slow-turnover catalyst that initiates DNA demethylation in a distributive fashion.
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article científic
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bilimsel makale
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scientific article published on 13 May 2009
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ROS1 5-methylcytosine DNA glyc ...... ion in a distributive fashion.
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ROS1 5-methylcytosine DNA glyc ...... ion in a distributive fashion.
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ROS1 5-methylcytosine DNA glyc ...... ion in a distributive fashion.
@en
ROS1 5-methylcytosine DNA glyc ...... ion in a distributive fashion.
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ROS1 5-methylcytosine DNA glyc ...... ion in a distributive fashion.
@en
ROS1 5-methylcytosine DNA glyc ...... ion in a distributive fashion.
@nl
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ROS1 5-methylcytosine DNA glyc ...... ion in a distributive fashion.
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María Isabel Ponferrada-Marín
Rafael R Ariza
Teresa Roldán-Arjona
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P304
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10.1093/NAR/GKP390
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P577
2009-05-13T00:00:00Z