Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells - Wikidata - awgldk - TriplyDB

Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells

Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells

http://www.wikidata.org/entity/Q37273851

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Pathogenic triad in COPD: oxidative stress, protease-antiprotease imbalance, and inflammation Potent Elastase Inhibitors from Cyanobacteria: Structural Basis and Mechanisms Mediating Cytoprotective and Anti-Inflammatory Effects in Bronchial Epithelial Cells Sarsasapogenin-AA13 inhibits LPS-induced inflammatory responses in macrophage cells in vitro and relieves dimethylbenzene-induced ear edema in mice Thrombin increases lung fibroblast survival while promoting alveolar epithelial cell apoptosis via the endoplasmic reticulum stress marker, CCAAT enhancer-binding homologous protein Role of protease-activated receptor-2 on cell death and DNA fragmentation in Helicobacter pylori-infected gastric epithelial cells.Elastase induces lung epithelial cell autophagy through placental growth factor: a new insight of emphysema pathogenesis PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema Pathogenesis of indirect (secondary) acute lung injury.Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2)Serine proteases degrade airway mucins in cystic fibrosis.Hypoxia sensitization of hepatocytes to neutrophil elastase-mediated cell death depends on MAPKs and HIF-1α.Molecular and cellular mechanisms of pulmonary fibrosis.Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?Transepithelial migration of neutrophils: mechanisms and implications for acute lung injury Elastase induced lung epithelial cell apoptosis and emphysema through placenta growth factor.Oxidized {alpha}1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema.Neutrophil-mediated activation of epithelial protease-activated receptors-1 and -2 regulates barrier function and transepithelial migration.Leukocyte elastase induces lung epithelial apoptosis via a PAR-1-, NF-kappaB-, and p53-dependent pathway.Alveolar epithelial and endothelial cell apoptosis in emphysema: what we know and what we need to know.Analysis of the protective biochemical and pathologic effects of aminoguanidine on an experimental aspiration pneumonitis model induced by bile acids.The coagulation factor Xa/protease activated receptor-2 axis in the progression of liver fibrosis: a multifaceted paradigm.Secretory leukocyte protease inhibitor and elafin/trappin-2: versatile mucosal antimicrobials and regulators of immunity.Roles of proteolysis in regulation of GPCR function.Apoptotic process in cystic fibrosis cells.Effects of elastase inhibitor on the epithelial cell apoptosis in bleomycin-induced pulmonary fibrosis.N-linked glycosylation regulates human proteinase-activated receptor-1 cell surface expression and disarming via neutrophil proteinases and thermolysin.Thrombin and TNF-alpha/IL-1beta synergistically induce fibroblast-mediated collagen gel degradation.Alpha-1 Antitrypsin Mitigates the Inhibition of Airway Epithelial Cell Repair by Neutrophil Elastase.Increased expression of senescence markers in cystic fibrosis airways Absence of proteinase-activated receptor-1 signaling in mice confers protection from fMLP-induced goblet cell metaplasia.Distinct functions of activated protein C differentially attenuate acute kidney injury.Matrix Metalloprotease-1 and Elastase Are Novel Uterotonic Agents Acting Through Protease-Activated Receptor 1.Administration of a specific inhibitor of neutrophil elastase attenuates pulmonary fibrosis after acute lung injury in mice.Mitochondrial dysfunctions in myalgic encephalomyelitis/chronic fatigue syndrome explained by activated immuno-inflammatory, oxidative and nitrosative stress pathways.Alpha1-antitrypsin suppresses TNF-alpha and MMP-12 production by cigarette smoke-stimulated macrophages.Protease-activated receptor (Par)1 alters bioelectric properties of distal lung epithelia without compromising barrier function.Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice Glycosaminoglycans Modify Elastase Action In Vitro and Enhance Elastase-Induced Cell Death in Cultured Fibroblasts

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Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells

http://www.wikidata.org/entity/Q37273851

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article scientifique

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bilimsel makale

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scientific article published on 12 May 2005

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vedecký článok

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Proteinase-activated receptor- ...... of human lung epithelial cells

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Proteinase-activated receptor- ...... f human lung epithelial cells.

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Proteinase-activated receptor- ...... of human lung epithelial cells

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Proteinase-activated receptor- ...... of human lung epithelial cells

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Proteinase-activated receptor- ...... f human lung epithelial cells.

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RCMB.2005-0109OC

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American Journal of Respiratory Cell and Molecular Biology

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Proteinase-activated receptor- ...... of human lung epithelial cells

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Christopher A G McCulloch

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Chung-Wai Chow

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Eric Vachon

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Gregory P Downey

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Hedy H Ginzberg

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John Marshall

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Maria Teresa Herrera Abreu

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Morley D Hollenberg

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Theo J Moraes

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Tomoko Suzuki

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P2860

Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathway

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome

Marked alveolar apoptosis/proliferation imbalance in end-stage emphysema

Science review: apoptosis in acute lung injury

Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis.

ILPIP, a novel anti-apoptotic protein that enhances XIAP-mediated activation of JNK1 and protection against apoptosis

Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells

Mitochondrial K(ATP) channel activation reduces anoxic injury by restoring mitochondrial membrane potential

Death receptors: signaling and modulation

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231-247

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10.1165/RCMB.2005-0109OC

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3

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33

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Michael Matthay

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2005-05-12T00:00:00Z

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15891109

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2715314

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