Interval-specific congenic lines reveal quantitative trait Loci with penetrant lyme arthritis phenotypes on chromosomes 5, 11, and 12.

Interval-specific congenic lines reveal quantitative trait Loci with penetrant lyme arthritis phenotypes on chromosomes 5, 11, and 12.

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http://www.wikidata.org/entity/Q37274879
Forward genetic approaches for elucidation of novel regulators of Lyme arthritis severityLysosomal β-glucuronidase regulates Lyme and rheumatoid arthritis severity.Congenic strains provide evidence that a mapped locus on chromosome 15 influences excitotoxic cell deathBorrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/B×N serum transfer arthritis through intrinsic control of type I IFN production.Pristane-induced arthritis loci interact with the Slc11a1 gene to determine susceptibility in mice selected for high inflammationHigh-throughput genotyping of advanced congenic lines by high resolution melting analysis for identification of Bbaa2, a QTL controlling Lyme arthritis.The Lyme disease spirochete Borrelia burgdorferi utilizes multiple ligands, including RNA, for interferon regulatory factor 3-dependent induction of type I interferon-responsive genesEndothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected joint tissue.Genetic Control of Lyme Arthritis by Borrelia burgdorferi Arthritis-Associated Locus 1 Is Dependent on Localized Differential Production of IFN-β and Requires Upregulation of Myostatin.
P2860

Interval-specific congenic lines reveal quantitative trait Loci with penetrant lyme arthritis phenotypes on chromosomes 5, 11, and 12.

Item
http://www.wikidata.org/entity/Q37274879
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Interval-specific congenic lin ...... on chromosomes 5, 11, and 12.
@en
Interval-specific congenic lin ...... on chromosomes 5, 11, and 12.
@nl
type
label
Interval-specific congenic lin ...... on chromosomes 5, 11, and 12.
@en
Interval-specific congenic lin ...... on chromosomes 5, 11, and 12.
@nl
prefLabel
Interval-specific congenic lin ...... on chromosomes 5, 11, and 12.
@en
Interval-specific congenic lin ...... on chromosomes 5, 11, and 12.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932
P356
P1433
P1476
Interval-specific congenic lin ...... on chromosomes 5, 11, and 12.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P932