In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice.
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Thyroid hormone signaling in vivo requires a balance between coactivators and corepressorsThyroid hormone regulation of metabolism3, 3'5 Triiodo L thyronine induces apoptosis in human breast cancer MCF-7 cells, repressing SMP30 expression through negative thyroid response elements.Mechanisms of thyroid hormone actionMethylsulfonylnitrobenzoates, a new class of irreversible inhibitors of the interaction of the thyroid hormone receptor and its obligate coactivators that functionally antagonizes thyroid hormone.The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axisThyroid hormone receptors and resistance to thyroid hormone disorders.Novel mechanism of positive versus negative regulation by thyroid hormone receptor β1 (TRβ1) identified by genome-wide profiling of binding sites in mouse liver.Thyroid hormone and estradiol have overlapping effects on kidney glutathione S-transferase-α gene expression.Synthesis and evaluation of methylsulfonylnitrobenzamides (MSNBAs) as inhibitors of the thyroid hormone receptor-coactivator interaction.Synthesis and evaluation of sulfonylnitrophenylthiazoles (SNPTs) as thyroid hormone receptor-coactivator interaction inhibitors.Hypothalamus-Pituitary-Thyroid Axis.Variable clinical presentation and outcome in pediatric patients with resistance to thyroid hormone (RTH).
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In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 30 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
In vivo interaction of steroid ...... ck-in and SRC-1 knockout mice.
@en
In vivo interaction of steroid receptor coactivator
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type
label
In vivo interaction of steroid ...... ck-in and SRC-1 knockout mice.
@en
In vivo interaction of steroid receptor coactivator
@nl
prefLabel
In vivo interaction of steroid ...... ck-in and SRC-1 knockout mice.
@en
In vivo interaction of steroid receptor coactivator
@nl
P2093
P2860
P356
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P1476
In vivo interaction of steroid ...... ck-in and SRC-1 knockout mice.
@en
P2093
Charles Goodwin
Danielle S Machado
Fredric E Wondisford
Manuela Alonso
Roy E Weiss
Samuel Refetoff
Tania Ortiga-Carvalho
Xiaohui Liao
P2860
P304
P356
10.1210/EN.2009-0093
P407
P577
2009-04-30T00:00:00Z