Chronic toxicity and carcinogenicity studies of chromium picolinate monohydrate administered in feed to F344/N rats and B6C3F1 mice for 2 years
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Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's diseaseChromium is not an essential trace element for mammals: effects of a "low-chromium" dietAssessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humansApplication of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromiumEffects of chromium picolinate on glycemic control and kidney of the obese Zucker ratChromium and genomic stabilityThe need for combined inorganic, biochemical, and nutritional studies of chromium(III).Exposure to hexavalent chromium resulted in significantly higher tissue chromium burden compared with trivalent chromium following similar oral doses to male F344/N rats and female B6C3F1 mice.Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water.Chromium in drinking water: sources, metabolism, and cancer risksEvaluation of the acute oral toxicity class of trinuclear chromium(III) glycinate complex in ratArsenic and chromium in drinking water promote tumorigenesis in a mouse colitis-associated colorectal cancer model and the potential mechanism is ROS-mediated Wnt/β-catenin signaling pathway.Renal and glycemic effects of high-dose chromium picolinate in db/db mice: assessment of DNA damage.Risk of Type 2 Diabetes Is Lower in US Adults Taking Chromium-Containing Supplements.Opinion controversy to chromium picolinate therapy's safety and efficacy: ignoring 'anecdotes' of case reports or recognising individual risks and new guidelines urgency to introduce innovation by predictive diagnostics?Reevaluation and Classification of Duodenal Lesions in B6C3F1 Mice and F344 Rats from 4 Studies of Hexavalent Chromium in Drinking Water.14-Day Toxicity Studies of Tetravalent and Pentavalent Vanadium Compounds in Harlan Sprague Dawley Rats and B6C3F1/N Mice via Drinking Water Exposure.Metal-based anti-diabetic drugs: advances and challenges.Different roles of ROS and Nrf2 in Cr(VI)-induced inflammatory responses in normal and Cr(VI)-transformed cellsEvaluation of oxidative stress and DNA damage in cement and tannery workers in Egypt.Carcinogenicity of chromium and chemoprevention: a brief updateThe Effects of Supplementary Cr3 (Chromium(III) Propionate Complex) on the Mineral Status in Healthy Female RatsFunctional proteomics reveals hepatotoxicity and the molecular mechanisms of different forms of chromium delivered by skin administration.Chromium nitrate as a source of chromium added for nutritional purposes to food supplementsChromium(III) lactate trihydrate as a source of chromium added for nutritional purposes to food supplementsChromium picolinate, zinc picolinate and zinc picolinate dihydrate added for nutritional purposes in food supplementsScientific Opinion on the safety of trivalent chromium as a nutrient added for nutritional purposes to foodstuffs for particular nutritional uses and foods intended for the general population (including food supplements)Scientific Opinion on the safety of chromium picolinate as a source of chromium added for nutritional purposes to foodstuff for particular nutritional uses and to foods intended for the general population[Cr3O(O2CCH2CH3)6(H2O)3]NO3·H2O (Cr3) Toxicity Potential in Bacterial and Mammalian Cells.Evaluation of the Reproductive Toxicity, Glycometabolism, Glycometabolism-Related Enzyme Levels and Lipid Metabolism of Chromium Malate Supplementation in Sprague-Dawley Rats.The Effects of High Dietary Doses of Chromium(III) Complex with Propionic Acid on Nutritional and Selected Blood Indices in Healthy Female Rats.Mechanistic insights from the NTP studies of chromium.Potential of chromium(III) picolinate for reproductive or developmental toxicity following exposure of male CD-1 mice prior to mating.Biochemical Mechanisms
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Chronic toxicity and carcinogenicity studies of chromium picolinate monohydrate administered in feed to F344/N rats and B6C3F1 mice for 2 years
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 08 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Chronic toxicity and carcinoge ...... ts and B6C3F1 mice for 2 years
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Chronic toxicity and carcinoge ...... s and B6C3F1 mice for 2 years.
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type
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Chronic toxicity and carcinoge ...... ts and B6C3F1 mice for 2 years
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Chronic toxicity and carcinoge ...... s and B6C3F1 mice for 2 years.
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Chronic toxicity and carcinoge ...... ts and B6C3F1 mice for 2 years
@en
Chronic toxicity and carcinoge ...... s and B6C3F1 mice for 2 years.
@nl
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P1476
Chronic toxicity and carcinoge ...... ts and B6C3F1 mice for 2 years
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B J Collins
D E Malarkey
G E Kissling
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P304
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10.1016/J.FCT.2009.01.006
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2009-01-08T00:00:00Z