Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53.
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Pyridinoacridine alkaloids of marine origin: NMR and MS spectral data, synthesis, biosynthesis and biological activityTargeting the ubiquitin pathway for cancer treatmentEvaluation of pyridoacridine alkaloids in a zebrafish phenotypic assay.Marine Pyridoacridine Alkaloids: Biosynthesis and Biological Activities.Discovery of Mdm2-MdmX E3 ligase inhibitors using a cell-based ubiquitination assay.Dual targeting of MDM2 with a novel small-molecule inhibitor overcomes TRAIL resistance in cancer.Natural products targeting the p53-MDM2 pathway and mutant p53: Recent advances and implications in cancer medicine
P2860
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P2860
Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 14 October 2008
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Discovery of new pyridoacridin ...... ity of Hdm2 and stabilize p53.
@en
Discovery of new pyridoacridin ...... ity of Hdm2 and stabilize p53.
@nl
type
label
Discovery of new pyridoacridin ...... ity of Hdm2 and stabilize p53.
@en
Discovery of new pyridoacridin ...... ity of Hdm2 and stabilize p53.
@nl
prefLabel
Discovery of new pyridoacridin ...... ity of Hdm2 and stabilize p53.
@en
Discovery of new pyridoacridin ...... ity of Hdm2 and stabilize p53.
@nl
P2093
P2860
P1476
Discovery of new pyridoacridin ...... ity of Hdm2 and stabilize p53.
@en
P2093
Allan M Weissman
Barry R O'Keefe
Carrie J Saucedo
James B McMahon
Jason A Clement
Jirouta Kitagaki
Tawnya C McKee
P2860
P304
10022-10028
P356
10.1016/J.BMC.2008.10.024
P407
P577
2008-10-14T00:00:00Z