about
Mechanisms underlying helper T-cell plasticity: implications for immune-mediated disease.Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesisMeta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in AsiansCD3Z hypermethylation is associated with severe clinical manifestations in systemic lupus erythematosus and reduces CD3ζ-chain expression in T cells.Decreased mRNA expression levels of DNA methyltransferases type 1 and 3A in systemic lupus erythematosus.Metabolic control of the epigenome in systemic Lupus erythematosus.DNA methylation dysregulations in rheumatic heart valve disease.Oxidative stress, T cell DNA methylation, and lupus.Transcriptional and epigenetic control of T helper cell specification: molecular mechanisms underlying commitment and plasticity.Potential of epigenetic therapies in non-cancerous conditions.MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases.Promoter hypomethylation results in increased expression of protein phosphatase 2A in T cells from patients with systemic lupus erythematosus.cAMP-responsive element modulator (CREM)α protein induces interleukin 17A expression and mediates epigenetic alterations at the interleukin-17A gene locus in patients with systemic lupus erythematosusCD4(+) T cells epigenetically modified by oxidative stress cause lupus-like autoimmunity in mice.The Upregulation of Genomic Imprinted DLK1-Dio3 miRNAs in Murine Lupus Is Associated with Global DNA Hypomethylation.Defective DNA repair and chromatin organization in patients with quiescent systemic lupus erythematosus.Methylation alterations of WT1 and homeobox genes in inflamed muscle biopsy samples from patients with untreated juvenile dermatomyositis suggest self-renewal capacity.Discovery of a novel genetic susceptibility locus on X chromosome for systemic lupus erythematosusFine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathwayElevated expression of miR-142-3p is related to the pro-inflammatory function of monocyte-derived dendritic cells in SLE.Epigenetic dysregulation in systemic lupus erythematosus.Critical role of DNA methylation in the pathogenesis of systemic lupus erythematosus: new advances and future challenges.CREMα suppresses spleen tyrosine kinase expression in normal but not systemic lupus erythematosus T cells.The interaction between environmental triggers and epigenetics in autoimmunity.High expression levels of microRNA-629, microRNA-525-5p and microRNA-516a-3p in paediatric systemic lupus erythematosus.Hypermethylation of glucocorticoid receptor gene promoter results in glucocorticoid receptor gene low expression in peripheral blood mononuclear cells of patients with systemic lupus erythematosus.Systemic Lupus Erythematosus: Recent Concepts in Genomics, Pathogenetic Mechanisms, and TherapiesEffects of Major Epigenetic Factors on Systemic Lupus Erythematosus
P2860
Q27687830-89C27D8C-F549-4951-BFF5-D0D0D90CFFBFQ28589092-052917A7-F598-48E2-AA3B-84E1E167DAA1Q28943338-A9EB6DA3-A2A0-434D-B7D4-F8B0087E6C49Q33437524-D5F6C50A-3A38-4120-9480-3FCB0FAC1129Q33581089-E68E807B-D396-4066-8370-3C20E3B9D36EQ33664849-DE6774B9-EA9B-43D5-9DC1-6FC11F52BF7BQ33808656-AF4854E2-3096-45BB-8D7F-5D540BD7B797Q34077487-5ED46174-E80D-41A7-A372-183C6E85FC3BQ34245251-79AE634B-A873-475B-8900-CE2899618424Q34742578-CE2F7ACB-2270-4A87-B7B0-C24196FE8FE7Q34772318-B5F5C87B-62B4-40FA-9A4D-C6EDFAAAB436Q35143592-B023EF20-E874-4064-9E75-0B9B23F79620Q35604631-58C937A9-66B5-4FFE-B3C7-75CF8DBC0B2CQ35930396-17997495-DD6F-4CC7-B749-3D6F6EECC90EQ35986953-F684A599-4088-416A-9F00-4E58F1CD457AQ36095555-0704A382-D796-419C-9580-02F40ED31AA2Q36291269-FAE58D6E-9E2C-4826-946E-D92428DEF51BQ36346648-0A164A7B-0A12-4150-8934-939DFE07F1E5Q36595002-3903F4A1-D0FA-488C-A96B-3A13C6225F7BQ37048453-24FCE30A-C4AF-45B8-A2A5-369EBFBD37A5Q37419371-74E9B634-36FC-41C9-A7FE-F00EEFB5F934Q38152825-59C7E976-F2A2-4DBD-8056-E9032F41D71CQ38197135-199C2271-2286-46BC-B784-E67F32F6D12AQ40134093-1860F311-B499-41CF-91DD-455DF51341C0Q52719777-8E841FFA-4EC5-4498-A454-3C9D2A01D9D2Q53059794-4C376691-2400-42A2-8A43-F18AB975932BQ53532896-3B0096EA-4477-4CCD-988B-8FCCE99B81B1Q58690067-F8E6F71F-D0C7-4D39-9A7E-37EF2F65EF58Q58778275-F7D9C6D4-518C-4D74-8A22-A16817D032BE
P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Epigenetic mechanisms in lupus.
@en
Epigenetic mechanisms in lupus.
@nl
type
label
Epigenetic mechanisms in lupus.
@en
Epigenetic mechanisms in lupus.
@nl
prefLabel
Epigenetic mechanisms in lupus.
@en
Epigenetic mechanisms in lupus.
@nl
P2860
P1476
Epigenetic mechanisms in lupus.
@en
P2093
Bruce C Richardson
Dipak R Patel
P2860
P304
P356
10.1097/BOR.0B013E32833AE915
P577
2010-09-01T00:00:00Z