Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA.
about
Prp40 and early events in splice site definitionA mutation in a rare type of intron in a sodium-channel gene results in aberrant splicing and causes myotonia.Correct mRNA processing at a mutant TT splice donor in FANCC ameliorates the clinical phenotype in patients and is enhanced by delivery of suppressor U1 snRNAs.A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.U1 adaptors result in reduction of multiple pre-mRNA species principally by sequestering U1snRNPMolecular Basis and Therapeutic Strategies to Rescue Factor IX Variants That Affect Splicing and Protein FunctionThe pathogenicity of splicing defects: mechanistic insights into pre-mRNA processing inform novel therapeutic approaches.The spliceosome: a flexible, reversible macromolecular machine.Differentially expressed, variant U1 snRNAs regulate gene expression in human cellsTherapeutic activity of modified U1 core spliceosomal particlesInduction of antagonistic soluble decoy receptor tyrosine kinases by intronic polyA activation.U1 snRNP-Dependent Suppression of Polyadenylation: Physiological Role and Therapeutic Opportunities in Cancer.Lessons from non-canonical splicingThe contribution of pseudouridine to stabilities and structure of RNAs.U1 small nuclear RNA variants differentially form ribonucleoprotein particles in vitroIntronic features that determine the selection of the 3' splice site.Pick one, but be quick: 5' splice sites and the problems of too many choices.Insights into the U1 small nuclear ribonucleoprotein complex superfamily.Dynamics and consequences of spliceosome E complex formation.Determinants of RNA metabolism in the Schizosaccharomyces pombe genome.Noncanonical registers and base pairs in human 5' splice-site selection.Characterization of the Regulation of CD46 RNA Alternative Splicing.Chemical synthesis of U1 snRNA derivatives.An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects.Widespread recognition of 5' splice sites by noncanonical base-pairing to U1 snRNA involving bulged nucleotides.TRAP150 activates splicing in composite terminal exons.A mechanism underlying position-specific regulation of alternative splicing.Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers.Rules and tools to predict the splicing effects of exonic and intronic mutations.A splicing component adapted to gene silencing.
P2860
Q26780366-D84EA69A-E605-432F-8EFF-23A95A4AD696Q30584867-EB89F560-805B-4E4B-BD8F-4567371277D4Q34169373-3BD9A4F3-0833-42E9-95C7-02CE118686B0Q34341178-080E9656-DC8B-4AAC-926E-F62105EB0DDDQ35017819-51FB5A66-75E3-4640-8AD5-588344F2E3A5Q36030221-4738B0A9-CF03-4899-A204-C94CA83D95D3Q36410173-5AC3CB65-E570-4B34-A645-4809F99416CDQ36429942-0FE5A494-BBF1-49F5-9A8B-251BD2319357Q36580574-29BD58A0-5A1C-4879-AAA6-15F3A6112E01Q36768787-FF3A98F3-8416-493A-9581-1AAD88DC9A8FQ37194653-735D8E70-2239-4B5A-ABF5-EC0BD0A1D54CQ37304518-614D0C79-DACA-4342-BA87-E52B7C2CE561Q37499331-1910FBC5-450F-4379-930A-88504E27E5DEQ37631867-354112E9-3EC8-4477-AB30-64C6430D4BEBQ37719737-157CB18F-8D8F-4842-B913-A91F59BBC89AQ38027121-31F94163-7B80-4C68-B97E-A522A0D1996DQ38076663-79E79703-9181-4952-86EB-5F98C46CA0B9Q38255119-FC7D8FB4-C0FB-435B-A21D-F26D5E66DA1AQ38614549-CAB41474-D982-4CC6-8520-E4BFD3716097Q38669635-271F8A21-48F3-498A-A466-EDBBF3B1CE33Q38896235-B1BF3D6A-7545-4227-BAC9-A310A58B7A50Q40659030-FE7BDC84-0F69-435C-B583-6C01DD6D35C1Q41890046-7DFE7EB4-F12F-4443-A655-593172B81124Q42156108-E2A08114-7274-4A63-9748-8466D49383E6Q42177704-6A54C8B4-60B1-4700-8495-A49A63B82BB1Q42999207-E307B753-8142-48B9-9256-3710823F2382Q47134651-85475F46-7979-485D-B964-A5C5CDF98EABQ47142870-DA765DE0-F619-492C-9F74-02B898230E0BQ49832045-1A1A5B87-492A-4E79-8E19-BBD4760FFE26Q51777937-6C38CC93-95CE-4C75-B770-4FF8F06794E0
P2860
Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 25 January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA.
@en
Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA.
@nl
type
label
Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA.
@en
Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA.
@nl
prefLabel
Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA.
@en
Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA.
@nl
P2860
P356
P1476
Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA.
@en
P2860
P2888
P304
P356
10.1038/NSMB.1546
P577
2009-01-25T00:00:00Z