Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis.
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Role of CCK/gastrin receptors in gastrointestinal/metabolic diseases and results of human studies using gastrin/CCK receptor agonists/antagonists in these diseases.A genomewide search finds major susceptibility loci for gallbladder disease on chromosome 1 in Mexican Americans.Ursodeoxycholic acid improves gastrointestinal motility defects in gallstone patients.The mechanism of enterohepatic circulation in the formation of gallstone disease.Cholecystokinin elevates mouse plasma lipidsImpaired intestinal cholecystokinin secretion, a fascinating but overlooked link between coeliac disease and cholesterol gallstone disease.Impaired cholecystokinin-induced gallbladder emptying incriminated in spontaneous "black" pigment gallstone formation in germfree Swiss Webster mice.Estrogen induces two distinct cholesterol crystallization pathways by activating ERα and GPR30 in female mice.Lipid transport in cholecystokinin knockout mice.Mechanisms of disease: the genetic epidemiology of gallbladder stones.Ezetimibe prevents the formation of oestrogen-induced cholesterol gallstones in mice.Lack of endogenous cholecystokinin promotes cholelithogenesis in miceMechanisms of CCK signaling from gut to brain.Increased susceptibility to diet-induced gallstones in liver fatty acid binding protein knockout mice.Coordinate regulation of gallbladder motor function in the gut-liver axis.New insights into the molecular mechanism of intestinal fatty acid absorption.Telocytes: New Players in Gallstone Disease.Gallstones: how do we translate an old story into future therapy?Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8(-/-) mice.Weaving betaKlotho into bile acid metabolism.Endogenous elevation of plasma cholecystokinin does not prevent gallstones.Targeted disruption of the murine mucin gene 1 decreases susceptibility to cholesterol gallstone formation.Lack of the intestinal Muc1 mucin impairs cholesterol uptake and absorption but not fatty acid uptake in Muc1-/- mice.Cd36 knockout mice are protected against lithogenic diet-induced gallstones.Ezetimibe prevents cholesterol gallstone formation in mice.Targeted disruption of the murine CCK1 receptor gene reduces intestinal lipid-induced feedback inhibition of gastric function.Role of intestinal sterol transporters Abcg5, Abcg8, and Npc1l1 in cholesterol absorption in mice: gender and age effects.Functions of the Gallbladder.The cholecystokinin-1 receptor antagonist devazepide increases cholesterol cholelithogenesis in mice.Telocytes and interstitial cells of Cajal in the biliary system.The Impact of Egg Nutrient Composition and Its Consumption on Cholesterol Homeostasis
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Targeted disruption of the murine cholecystokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeted disruption of the mur ...... to cholesterol cholelithiasis.
@en
Targeted disruption of the mur ...... to cholesterol cholelithiasis.
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type
label
Targeted disruption of the mur ...... to cholesterol cholelithiasis.
@en
Targeted disruption of the mur ...... to cholesterol cholelithiasis.
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prefLabel
Targeted disruption of the mur ...... to cholesterol cholelithiasis.
@en
Targeted disruption of the mur ...... to cholesterol cholelithiasis.
@nl
P2093
P2860
P356
P1476
Targeted disruption of the mur ...... to cholesterol cholelithiasis.
@en
P2093
Alan S Kopin
David Q-H Wang
Frank Schmitz
Martin C Carey
P2860
P304
P356
10.1172/JCI16801
P407
P577
2004-08-01T00:00:00Z