A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR).
about
Rab1A is an mTORC1 activator and a colorectal oncogeneHigh-resolution yeast phenomics resolves different physiological features in the saline responseThe uses of genome-wide yeast mutant collectionsChemical genomics: what will it take and who gets to play?Candida glabrata: new tools and technologies-expanding the toolkitLST8 negatively regulates amino acid biosynthesis as a component of the TOR pathwayChromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR.Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast.Cell cycle progression in G1 and S phases is CCR4 dependent following ionizing radiation or replication stress in Saccharomyces cerevisiae.Urmylation: a ubiquitin-like pathway that functions during invasive growth and budding in yeast.Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmanninIdentification of Ald6p as the target of a class of small-molecule suppressors of FK506 and their use in network dissection.Nutrient regulates Tor1 nuclear localization and association with rDNA promoter.Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysisChemogenomics: an emerging strategy for rapid target and drug discoveryCcr4-not regulates RNA polymerase I transcription and couples nutrient signaling to the control of ribosomal RNA biogenesisInsulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activityUbiquitin and ubiquitin-like proteins as multifunctional signalsTOR signaling.Cell growth control: little eukaryotes make big contributions.A genome-wide over-expression screen identifies genes involved in phagocytosis in the human protozoan parasite, Entamoeba histolytica.Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae.Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method.Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae.The cytosolic thiouridylase CTU2 of Arabidopsis thaliana is essential for posttranscriptional thiolation of tRNAs and influences root developmentRobustness and evolvability in natural chemical resistance: identification of novel systems properties, biochemical mechanisms and regulatory interactions.Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast.The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses.The target of rapamycin (TOR) proteinsDissecting the gene network of dietary restriction to identify evolutionarily conserved pathways and new functional genes.A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damageDissection of a complex phenotype by functional genomics reveals roles for the yeast cyclin-dependent protein kinase Pho85 in stress adaptation and cell integrity.The Saccharomyces cerevisiae phosphatase activator RRD1 is required to modulate gene expression in response to rapamycin exposure.Loss of ypk1 function causes rapamycin sensitivity, inhibition of translation initiation and synthetic lethality in 14-3-3-deficient yeast.Statistical analysis reveals co-expression patterns of many pairs of genes in yeast are jointly regulated by interacting loci.Chemical genomics as an emerging paradigm for postgenomic drug discovery.Both the autophagy and proteasomal pathways facilitate the Ubp3p-dependent depletion of a subset of translation and RNA turnover factors during nitrogen starvation in Saccharomyces cerevisiae.Chemical genomics approach to identify genes associated with sensitivity to rapamycin in the fission yeast Schizosaccharomyces pombe.Inferring causal metabolic signals that regulate the dynamic TORC1-dependent transcriptomeMulti-functional regulation of 4E-BP gene expression by the Ccr4-Not complex
P2860
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P2860
A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR).
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
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2000年學術文章
@zh-hant
name
A chemical genomics approach t ...... et of rapamycin protein (TOR).
@en
A chemical genomics approach t ...... he target of rapamycin protein
@nl
type
label
A chemical genomics approach t ...... et of rapamycin protein (TOR).
@en
A chemical genomics approach t ...... he target of rapamycin protein
@nl
prefLabel
A chemical genomics approach t ...... et of rapamycin protein (TOR).
@en
A chemical genomics approach t ...... he target of rapamycin protein
@nl
P2093
P2860
P356
P1476
A chemical genomics approach t ...... get of rapamycin protein (TOR)
@en
P2093
P2860
P304
13227-13232
P356
10.1073/PNAS.240444197
P407
P50
P577
2000-11-01T00:00:00Z