Potential neurotoxicity of ketamine in the developing rat brain.
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Is ketamine a lifesaving agent in childhood acute severe asthma?Modeling anesthetic developmental neurotoxicity using human stem cellsDevelopmental origins of adult diseases and neurotoxicity: epidemiological and experimental studiesImpact of ketamine on learning and memory function, neuronal apoptosis and its potential association with miR-214 and PTEN in adolescent ratsJuvenile exposure to ketamine causes delayed emergence of EEG abnormalities during adulthood in miceChronic ketamine impairs fear conditioning and produces long-lasting reductions in auditory evoked potentials.Delayed emergence of behavioral and electrophysiological effects following juvenile ketamine exposure in miceUse of analgesic and sedative drugs in the NICU: integrating clinical trials and laboratory data.Neonatal ketamine exposure causes impairment of long-term synaptic plasticity in the anterior cingulate cortex of ratsChronic Ketamine Exposure Causes White Matter Microstructural Abnormalities in Adolescent Cynomolgus MonkeysAnaesthetics-induced neurotoxicity in developing brain: an update on preclinical evidence.Emerging model in anesthetic developmental neurotoxicity: human stem cells.Effects of intrathecal ketamine in the neonatal rat: evaluation of apoptosis and long-term functional outcomeEarly childhood general anaesthesia exposure and neurocognitive development.The effect of lidocaine on apoptotic neurodegeneration in the developing mouse brainIn vitro dose-dependent inhibition of the intracellular spontaneous calcium oscillations in developing hippocampal neurons by ketamine.Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys.Ketamine affects the neurogenesis of rat fetal neural stem progenitor cells via the PI3K/Akt-p27 signaling pathwayKetamine-induced neurotoxicity and changes in gene expression in the developing rat brain.Repeated exposure to anesthetic ketamine can negatively impact neurodevelopment in infants: a prospective preliminary clinical study.Repeated ketamine administration alters N-methyl-D-aspartic acid receptor subunit gene expression: implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans.Developmental neurotoxicity screening using human embryonic stem cells.Neurocognitive Changes after Sustained Ketamine Administration in Children with Chronic Pain.Advanced pre-clinical research approaches and models to studying pediatric anesthetic neurotoxicityFeasibility and pilot study of the Pediatric Anesthesia NeuroDevelopment Assessment (PANDA) projectKetamine alters the neurogenesis of rat cortical neural stem progenitor cells.Ketamine-induced neuronal damage and altered N-methyl-D-aspartate receptor function in rat primary forebrain culture.The blockade of NMDA receptor ion channels by ketamine is enhanced in developing rat cortical neurons.Ketamine enhances human neural stem cell proliferation and induces neuronal apoptosis via reactive oxygen species-mediated mitochondrial pathwayAnesthesia and analgesia in the NICU.Ketamine exposure during embryogenesis inhibits cellular proliferation in rat fetal cortical neurogenic regionsKetamine induces toxicity in human neurons differentiated from embryonic stem cells via mitochondrial apoptosis pathway.Neurotoxicity of general anesthetics: cause for concern?Neurodevelopmental risks of pediatric anesthesia: what do we know, and what should we do?Application of microPET imaging approaches in the study of pediatric anesthetic-induced neuronal toxicity.Preclinical assessment of ketamine.Developmental anesthetic neurotoxicity: from animals to humans?Utilization of neural stem cell-derived models to study anesthesia-related toxicity and preventative approaches.Anesthetic neurotoxicity: what to tell the parents?Inhibition of acetylcholinesterase modulates NMDA receptor antagonist mediated alterations in the developing brain.
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Potential neurotoxicity of ketamine in the developing rat brain.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Potential neurotoxicity of ketamine in the developing rat brain.
@en
Potential neurotoxicity of ketamine in the developing rat brain.
@nl
type
label
Potential neurotoxicity of ketamine in the developing rat brain.
@en
Potential neurotoxicity of ketamine in the developing rat brain.
@nl
prefLabel
Potential neurotoxicity of ketamine in the developing rat brain.
@en
Potential neurotoxicity of ketamine in the developing rat brain.
@nl
P2093
P2860
P356
P1476
Potential neurotoxicity of ketamine in the developing rat brain.
@en
P2093
Cheng Wang
Daniel R Doerge
Joseph P Hanig
Merle G Paule
Natalya Sadovova
Nathan C Twaddle
Tucker A Patterson
William Slikker
Xiaoju Zou
P2860
P304
P356
10.1093/TOXSCI/KFN270
P577
2009-01-06T00:00:00Z