Survival motor neuron protein modulates neuron-specific apoptosis. - Wikidata - awgldk - TriplyDB

Survival motor neuron protein modulates neuron-specific apoptosis.

Survival motor neuron protein modulates neuron-specific apoptosis.

http://www.wikidata.org/entity/Q37292520

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ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies.The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism Age-dependent resistance to lethal alphavirus encephalitis in mice: analysis of gene expression in the central nervous system and identification of a novel interferon-inducible protective gene, mouse ISG12.Minute virus of mice NS1 interacts with the SMN protein, and they colocalize in novel nuclear bodies induced by parvovirus infection Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpain Direct interaction of the spinal muscular atrophy disease protein SMN with the small nucleolar RNA-associated protein fibrillarin.Spinal muscular atrophy: new and emerging insights from model mice Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy Prediction of protease substrates using sequence and structure features.Genetic and expression studies of SMN2 gene in Russian patients with spinal muscular atrophy type II and III A direct interaction between the survival motor neuron protein and p53 and its relationship to spinal muscular atrophy.Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy.SMN regulates axonal local translation via miR-183/mTOR pathway Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: evidence for involvement of splicing regulatory proteins.Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis.Targeting intrinsically disordered proteins in neurodegenerative and protein dysfunction diseases: another illustration of the D(2) concept.Therapeutics development for spinal muscular atrophy.Severe impairment of male reproductive organ development in a low SMN expressing mouse model of spinal muscular atrophy Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis.Update on gene and stem cell therapy approaches for spinal muscular atrophy.Spinal muscular atrophy and the antiapoptotic role of survival of motor neuron (SMN) protein.Disease modeling and drug screening for neurological diseases using human induced pluripotent stem cells.A sensitive assay for measuring SMN mRNA levels in peripheral blood and in muscle samples of patients affected with spinal muscular atrophy.Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy.Identification of genes involved in the host response to neurovirulent alphavirus infection.SMN protects cells against mutant SOD1 toxicity by increasing chaperone activity.Refined characterization of the expression and stability of the SMN gene products.Neuroprotective Effect of Non-viral Gene Therapy Treatment Based on Tetanus Toxin C-fragment in a Severe Mouse Model of Spinal Muscular Atrophy Survival motor neuron (SMN) protein interacts with transcription corepressor mSin3A.Neuroblastoma in a Patient With Spinal Muscular Atrophy Type I: Is It Just a Coincidence?Gender-Specific Amelioration of SMA Phenotype upon Disruption of a Deep Intronic Structure by an Oligonucleotide.Implication of fetal SMN2 expression in type I SMA pathogenesis: protection or pathological gain of function?Downregulation of Bcl-2 proteins in type I spinal muscular atrophy motor neurons during fetal development.Quantitative proteomic analysis identifies proteins and pathways related to neuronal development in differentiated SH-SY5Y neuroblastoma cells.A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein

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P2860

Survival motor neuron protein modulates neuron-specific apoptosis.

http://www.wikidata.org/entity/Q37292520

description

2000 nî lūn-bûn

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2000年の論文

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2000年学术文章

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2000年学术文章

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2000年学术文章

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2000年学术文章

@zh-my

2000年学术文章

@zh-sg

2000年學術文章

@yue

2000年學術文章

@zh

2000年學術文章

@zh-hant

name

Survival motor neuron protein modulates neuron-specific apoptosis.

@en

Survival motor neuron protein modulates neuron-specific apoptosis.

@nl

type

label

Survival motor neuron protein modulates neuron-specific apoptosis.

@en

Survival motor neuron protein modulates neuron-specific apoptosis.

@nl

prefLabel

Survival motor neuron protein modulates neuron-specific apoptosis.

@en

Survival motor neuron protein modulates neuron-specific apoptosis.

@nl

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P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Survival motor neuron protein modulates neuron-specific apoptosis.

@en

P2093

B N Chau

http://www.w3.org/2001/XMLSchema#string

D A Kerr

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J M Hardwick

http://www.w3.org/2001/XMLSchema#string

J P Nery

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R J Traystman

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P2860

Characterization of a gene encoding survival motor neuron (SMN)-related protein, a constituent of the spliceosome complex

A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing

Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins

The SMN-SIP1 complex has an essential role in spliceosomal snRNP biogenesis

A novel nuclear structure containing the survival of motor neurons protein

A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy

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13312-13317

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10.1073/PNAS.230364197

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24

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97

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11078511

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apoptotic process

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27221

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