From hatching to dispatching: the multiple cellular roles of the Hsp70 molecular chaperone machinery.
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Features of protein-protein interactions that translate into potent inhibitors: topology, surface area and affinityModulation and elimination of yeast prions by protein chaperones and co-chaperonesMetabolic and chaperone gene loss marks the origin of animals: evidence for Hsp104 and Hsp78 chaperones sharing mitochondrial enzymes as clientsCrystal Structure of DnaK Protein Complexed with Nucleotide Exchange Factor GrpE in DnaK Chaperone System: INSIGHT INTO INTERMOLECULAR COMMUNICATIONCDK-dependent Hsp70 Phosphorylation controls G1 cyclin abundance and cell-cycle progressionInvestigating Apoptozole as a Chemical Probe for HSP70 InhibitionBAG3 protein is overexpressed in human glioblastoma and is a potential target for therapyHSPA8/HSC70 chaperone protein: structure, function, and chemical targeting.A review of multi-domain and flexible molecular chaperones studies by small-angle X-ray scattering.Proteomic characterization of an isolated fraction of synthetic proteasome inhibitor (PSI)-induced inclusions in PC12 cells might offer clues to aggresomes as a cellular defensive response against proteasome inhibition by PSI.Pathways of allosteric regulation in Hsp70 chaperones.The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.Heat shock protein 70 (hsp70) as an emerging drug target.Heteromeric complexes of heat shock protein 70 (HSP70) family members, including Hsp70B', in differentiated human neuronal cells.Regulation of FSP27 protein stability by AMPK and HSC70.Chemical screens against a reconstituted multiprotein complex: myricetin blocks DnaJ regulation of DnaK through an allosteric mechanismMonocyte to macrophage differentiation goes along with modulation of the plasmalogen pattern through transcriptional regulation.Single methyl group determines prion propagation and protein degradation activities of yeast heat shock protein (Hsp)-70 chaperones Ssa1p and Ssa2pThe Hsp70 and Hsp40 chaperones influence microtubule stability in ChlamydomonasHsp70 clears misfolded kinases that partitioned into distinct quality-control compartments.Non-Lethal Heat Shock of the Asian Green Mussel, Perna viridis, Promotes Hsp70 Synthesis, Induces Thermotolerance and Protects Against Vibrio Infection.Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase.Computational Analysis of Residue Interaction Networks and Coevolutionary Relationships in the Hsp70 Chaperones: A Community-Hopping Model of Allosteric Regulation and CommunicationAge-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevityInfluence of Hsp70s and their regulators on yeast prion propagationPharmacological targeting of the Hsp70 chaperone.Hsp70 protein complexes as drug targets.The control of spindle length by Hsp70 and Hsp110 molecular chaperones.Molecular analysis of Hsp70 mechanisms in plants and their function in response to stress.Hsp70 - a master regulator in protein degradation.The culinary-medicinal mushroom Coprinus comatus as a natural antiandrogenic modulator.Role of low native state kinetic stability and interaction of partially unfolded states with molecular chaperones in the mitochondrial protein mistargeting associated with primary hyperoxaluria.MARCKS and HSP70 interactions regulate mucin secretion by human airway epithelial cells in vitro.Synthetic lethal interactions in yeast reveal functional roles of J protein co-chaperonesA Rhodiola rosea root extract protects skeletal muscle cells against chemically induced oxidative stress by modulating heat shock protein 70 (HSP70) expression.Melusin protects from cardiac rupture and improves functional remodelling after myocardial infarction.Formal Models of Biological Systems.Crohn's Disease Variants of Nod2 Are Stabilized by the Critical Contact Region of Hsp70.Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease.Heat Shock Cognate 70 Inhibitor, VER-155008, Reduces Memory Deficits and Axonal Degeneration in a Mouse Model of Alzheimer's Disease.
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From hatching to dispatching: the multiple cellular roles of the Hsp70 molecular chaperone machinery.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 October 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
From hatching to dispatching: ...... molecular chaperone machinery.
@en
From hatching to dispatching: ...... molecular chaperone machinery.
@nl
type
label
From hatching to dispatching: ...... molecular chaperone machinery.
@en
From hatching to dispatching: ...... molecular chaperone machinery.
@nl
prefLabel
From hatching to dispatching: ...... molecular chaperone machinery.
@en
From hatching to dispatching: ...... molecular chaperone machinery.
@nl
P2093
P356
P1476
From hatching to dispatching: ...... molecular chaperone machinery.
@en
P2093
Eirini Meimaridou
J Paul Chapple
Sakina B Gooljar
P356
10.1677/JME-08-0116
P577
2008-10-13T00:00:00Z