An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host.
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A portrait of the transcriptome of the neglected trematode, Fasciola gigantica--biological and biotechnological implicationsUnlocking the transcriptomes of two carcinogenic parasites, Clonorchis sinensis and Opisthorchis viverriniWhole-genome sequence of Schistosoma haematobiumStimulating Neoblast-Like Cell Proliferation in Juvenile Fasciola hepatica Supports Growth and Progression towards the Adult Phenotype In VitroCysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater PlanariaIdentification of Chalcones as Fasciola hepatica Cathepsin L Inhibitors Using a Comprehensive Experimental and Computational ApproachPeroxiredoxin-1 from the Human Hookworm Ancylostoma ceylanicum Forms a Stable Oxidized Decamer and Is Covalently Inhibited by Conoidin AA prospective view of animal and human FasciolosisA family of helminth molecules that modulate innate cell responses via molecular mimicry of host antimicrobial peptidesThe transcriptome analysis of Strongyloides stercoralis L3i larvae reveals targets for intervention in a neglected diseaseA research agenda for helminth diseases of humans: basic research and enabling technologies to support control and elimination of helminthiasesInsights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico ApproachesInsights into SCP/TAPS proteins of liver flukes based on large-scale bioinformatic analyses of sequence datasetsGenetic characterization, species differentiation and detection of Fasciola spp. by molecular approachesFasciolosis in South America: epidemiology and control challenges.TranSeqAnnotator: large-scale analysis of transcriptomic data.The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution.Survey of transcripts expressed by the invasive juvenile stage of the liver fluke Fasciola hepaticaSecretome: clues into pathogen infection and clinical applications.Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepaticaTowards delineating functions within the fasciola secreted cathepsin l protease family by integrating in vivo based sub-proteomics and phylogenetics.Collagenolytic activities of the major secreted cathepsin L peptidases involved in the virulence of the helminth pathogen, Fasciola hepatica.Secreted cysteine proteases of the carcinogenic liver fluke, Opisthorchis viverrini: regulation of cathepsin F activation by autocatalysis and trans-processing by cathepsin BMolecular cloning, expression, and immunolocalization of protein disulfide isomerase in excretory-secretory products from Clonorchis sinensis.RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro.Helminth secretome database (HSD): a collection of helminth excretory/secretory proteins predicted from expressed sequence tags (ESTs).Systems biology studies of adult paragonimus lung flukes facilitate the identification of immunodominant parasite antigensIn-depth proteomic and glycomic analysis of the adult-stage Cooperia oncophora excretome/secretome.Secreted proteins from the helminth Fasciola hepatica inhibit the initiation of autoreactive T cell responses and prevent diabetes in the NOD mouseExtracellular vesicles from parasitic helminths contain specific excretory/secretory proteins and are internalized in intestinal host cellsThe secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverriniFasciola hepatica fatty acid binding protein induces the alternative activation of human macrophages.Transcriptome profiles of the protoscoleces of Echinococcus granulosus reveal that excretory-secretory products are essential to metabolic adaptationDifferential activation of diverse glutathione transferases of Clonorchis sinensis in response to the host bile and oxidative stressors.Extracellular vesicles in parasitic diseasesDissecting the active site of the collagenolytic cathepsin L3 protease of the invasive stage of Fasciola hepatica.Cloning and characterization of a 2-cys peroxiredoxin in the pine wood nematode, Bursaphelenchus xylophilus, a putative genetic factor facilitating the infestation.Generating a detailed protein profile of Fasciola hepatica during the chronic stage of infection in cattle.Proteomic identification of potential Clonorchis sinensis excretory/secretory products capable of binding and activating human hepatic stellate cells.Fasciola hepatica vaccine: we may not be there yet but we're on the right road
P2860
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P2860
An integrated transcriptomics and proteomics analysis of the secretome of the helminth pathogen Fasciola hepatica: proteins associated with invasion and infection of the mammalian host.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
An integrated transcriptomics ...... fection of the mammalian host.
@en
An integrated transcriptomics ...... fection of the mammalian host.
@nl
type
label
An integrated transcriptomics ...... fection of the mammalian host.
@en
An integrated transcriptomics ...... fection of the mammalian host.
@nl
prefLabel
An integrated transcriptomics ...... fection of the mammalian host.
@en
An integrated transcriptomics ...... fection of the mammalian host.
@nl
P2860
P50
P1476
An integrated transcriptomics ...... nfection of the mammalian host
@en
P2093
John P Dalton
Ranjeeta Menon
P2860
P304
P356
10.1074/MCP.M900045-MCP200
P577
2009-05-14T00:00:00Z