Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.
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Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer TherapyGlioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic TargetsGlioblastoma Stem Cells Microenvironment: The Paracrine Roles of the Niche in Drug and RadioresistancePerspectives in the treatment of pancreatic adenocarcinomaRecapitulating the Tumor Ecosystem Along the Metastatic Cascade Using 3D Culture ModelsA metabolic perspective of Peto's paradox and cancerThe clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunitiesCrystal Structure of the Sema-PSI Extracellular Domain of Human RON Receptor Tyrosine KinaseRedox regulation of store-operated Ca2+ entryHypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cellsHypoxia and cytoplasmic alkalinization upregulate growth hormone expression in lymphocytesAcidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitorsTargeting carbonic anhydrase IX improves the anti-cancer efficacy of mTOR inhibitorsCorrelation of expression of hypoxia-related proteins with prognosis in oral squamous cell carcinoma patients.Gold Nanotheranostics: Proof-of-Concept or Clinical Tool?Elucidation of how cancer cells avoid acidosis through comparative transcriptomic data analysis.Acidic pH-targeted chitosan capped mesoporous silica coated gold nanorods facilitate detection of pancreatic tumors via multispectral optoacoustic tomographyCurrent views on cell metabolism in SDHx-related pheochromocytoma and paragangliomaUnderstanding the pharmacological properties of a metabolic PET tracer in prostate cancerAtrial natriuretic peptide: a magic bullet for cancer therapy targeting Wnt signaling and cellular pH regulatorsIn vivo pH in metabolic-defective Ras-transformed fibroblast tumors: key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH.Ascent to altitude as a weight loss method: the good and bad of hypoxia inducible factor activationAnticancer targets in the glycolytic metabolism of tumors: a comprehensive reviewHypoxia-adaptation involves mitochondrial metabolic depression and decreased ROS leakageEvolution of Tumor Metabolism might Reflect Carcinogenesis as a Reverse Evolution process (Dismantling of Multicellularity).Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cellspHLIP-FIRE, a cell insertion-triggered fluorescent probe for imaging tumors demonstrates targeted cargo delivery in vivo.Family of pH (low) insertion peptides for tumor targeting.Mitochondrial bioenergetics of metastatic breast cancer cells in response to dynamic changes in oxygen tension: effects of HIF-1αAcidic stress promotes a glioma stem cell phenotype.Metastasis-associated gene, mag-1 improves tumour microenvironmental adaptation and potentiates tumour metastasis.Global transcriptomic analysis of model human cell lines exposed to surface-modified gold nanoparticles: the effect of surface chemistry.Modulation of autophagic activity by extracellular pH.Hypoxia-induced acidosis uncouples the STIM-Orai calcium signaling complexFunctional interaction between responses to lactic acidosis and hypoxia regulates genomic transcriptional outputs.Tumor cell metabolism: an integral view.Inhibition of cancer cell proliferation and breast tumor targeting of pHLIP-monomethyl auristatin E conjugates.Regulation of acid-base transporters by reactive oxygen species following mitochondrial fragmentationThe pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions
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Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 08 December 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.
@en
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.
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type
label
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.
@en
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.
@nl
prefLabel
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.
@en
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.
@nl
P2860
P1476
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer.
@en
P2093
Johanna Chiche
M Christiane Brahimi-Horn
P2860
P304
P356
10.1111/J.1582-4934.2009.00994.X
P577
2009-12-08T00:00:00Z
2010-04-01T00:00:00Z