Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis

Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis

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http://www.wikidata.org/entity/Q37296767
Commensal microbes drive intestinal inflammation by IL-17-producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2.Effect of guanylate cyclase-C activity on energy and glucose homeostasisGut microbiome and anticancer immune response: really hot Sh*t!Plecanatide and dolcanatide, novel guanylate cyclase-C agonists, ameliorate gastrointestinal inflammation in experimental models of murine colitis.The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel diseaseExpression of guanylate cyclase-C, guanylin, and uroguanylin is downregulated proportionally to the ulcerative colitis disease activity index.GUCY2C ligand replacement to prevent colorectal cancer.Congenital secretory diarrhoea caused by activating germline mutations in GUCY2C.Pendrin, a novel transcriptional target of the uroguanylin system.cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium.GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome.GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress.Guanylate cyclase C reduces invasion of intestinal epithelial cells by bacterial pathogens.Sildenafil Suppresses Inflammation-Driven Colorectal Cancer in Mice.The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia
P2860

Guanylate cyclase C deficiency causes severe inflammation in a murine model of spontaneous colitis

Item
http://www.wikidata.org/entity/Q37296767
description
2013 nî lūn-bûn
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name
Guanylate cyclase C deficiency ...... e model of spontaneous colitis
@en
Guanylate cyclase C deficiency ...... model of spontaneous colitis.
@nl
type
label
Guanylate cyclase C deficiency ...... e model of spontaneous colitis
@en
Guanylate cyclase C deficiency ...... model of spontaneous colitis.
@nl
prefLabel
Guanylate cyclase C deficiency ...... e model of spontaneous colitis
@en
Guanylate cyclase C deficiency ...... model of spontaneous colitis.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Guanylate cyclase C deficiency ...... e model of spontaneous colitis
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0079180
P407
P433
P478
P50
P577
P5875
P698
P921
P932