Cathepsin L inhibition by the small molecule KGP94 suppresses tumor microenvironment enhanced metastasis associated cell functions of prostate and breast cancer cells
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An Active 32-kDa Cathepsin L Is Secreted Directly from HT 1080 Fibrosarcoma Cells and Not via Lysosomal Exocytosis.Modulation of the tumor vasculature and oxygenation to improve therapyCathepsin L targeting in cancer treatment.Cathepsin L inactivation leads to multimodal inhibition of prostate cancer cell dissemination in a preclinical bone metastasis model.Synthesis and biochemical evaluation of benzoylbenzophenone thiosemicarbazone analogues as potent and selective inhibitors of cathepsin L.Synthesis and Preclinical Evaluation of a Highly Improved Anticancer Prodrug Activated by Histone Deacetylases and Cathepsin L.Overexpression of Cathepsin L is associated with chemoresistance and invasion of epithelial ovarian cancer.Cathepsin L in tumor angiogenesis and its therapeutic intervention by the small molecule inhibitor KGP94.Metastasis review: from bench to bedside.Hypoxia: Signaling the Metastatic Cascade.Differential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cellsTRPM5 mediates acidic extracellular pH signaling and TRPM5 inhibition reduces spontaneous metastasis in mouse B16-BL6 melanoma cells.Clinical Impact of Cystatin C/Cathepsin L and Follistatin/Activin A Systems in Breast Cancer Progression: A Preliminary Report.Gelatin Zymography Using Leupeptin for the Detection of Various Cathepsin L Forms.MicroRNA-1180 is associated with growth and apoptosis in prostate cancer via TNF receptor associated factor 1 expression regulation and nuclear factor-κB signaling pathway activation.Stromal cells in breast cancer as a potential therapeutic target.
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P2860
Cathepsin L inhibition by the small molecule KGP94 suppresses tumor microenvironment enhanced metastasis associated cell functions of prostate and breast cancer cells
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 09 June 2013
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Cathepsin L inhibition by the ...... ostate and breast cancer cells
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Cathepsin L inhibition by the ...... state and breast cancer cells.
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type
label
Cathepsin L inhibition by the ...... ostate and breast cancer cells
@en
Cathepsin L inhibition by the ...... state and breast cancer cells.
@nl
prefLabel
Cathepsin L inhibition by the ...... ostate and breast cancer cells
@en
Cathepsin L inhibition by the ...... state and breast cancer cells.
@nl
P2860
P1476
Cathepsin L inhibition by the ...... ostate and breast cancer cells
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P2093
Dietmar W Siemann
P2860
P2888
P304
P356
10.1007/S10585-013-9590-9
P577
2013-06-09T00:00:00Z