Alternative splicing of Cav1.2 channel exons in smooth muscle cells of resistance-size arteries generates currents with unique electrophysiological properties.
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The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialShould pharmacologists care about alternative splicing? IUPHAR Review 4The calmodulin-binding, short linear motif, NSCaTE is conserved in L-type channel ancestors of vertebrate Cav1.2 and Cav1.3 channelsDisruption of K(2P)6.1 produces vascular dysfunction and hypertension in miceCa(v)1.2 splice variant with exon 9* is critical for regulation of cerebral artery diameter.Dihydropyridine-insensitive calcium currents contribute to function of small cerebral arteriesEugenol dilates rat cerebral arteries by inhibiting smooth muscle cell voltage-dependent calcium channels.Regulation of the mutually exclusive exons 8a and 8 in the CaV1.2 calcium channel transcript by polypyrimidine tract-binding protein.Ca(V)1.2 channel N-terminal splice variants modulate functional surface expression in resistance size artery smooth muscle cellsCa(V)3.2 channels and the induction of negative feedback in cerebral arteries.Contribution of transient and sustained calcium influx, and sensitization to depolarization-induced contractions of the intact mouse aortaIdentification of L- and T-type Ca2+ channels in rat cerebral arteries: role in myogenic tone developmentA naturally occurring truncated Cav1.2 α1-subunit inhibits Ca2+ current in A7r5 cells.Developmental origins of colon smooth muscle dysfunction in IBS-like ratsAberrant Splicing Promotes Proteasomal Degradation of L-type CaV1.2 Calcium Channels by Competitive Binding for CaVβ Subunits in Cardiac Hypertrophy.T-type calcium channels and vascular function: the new kid on the block?High affinity complexes of pannexin channels and L-type calcium channel splice-variants in human lung: Possible role in clevidipine-induced dyspnea relief in acute heart failure.Smooth Muscle Ion Channels and Regulation of Vascular Tone in Resistance Arteries and Arterioles.Ion channel mechanisms of rat tail artery contraction-relaxation by menthol involving, respectively, TRPM8 activation and L-type Ca2+ channel inhibition.Ca(v)2 channels mediate low and high voltage-activated calcium currents in Drosophila motoneurons.Characterization of CaV1.2 exon 33 heterozygous knockout mice and negative correlation between Rbfox1 and CaV1.2 exon 33 expressions in human heart failure.The voltage-dependent L-type Ca2+ (CaV1.2) channel C-terminus fragment is a bi-modal vasodilator.Measuring T-Type Calcium Channel Currents in Isolated Vascular Smooth Muscle Cells.
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P2860
Alternative splicing of Cav1.2 channel exons in smooth muscle cells of resistance-size arteries generates currents with unique electrophysiological properties.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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Alternative splicing of Cav1.2 ...... ectrophysiological properties.
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Alternative splicing of Cav1.2 ...... ectrophysiological properties.
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Alternative splicing of Cav1.2 ...... ectrophysiological properties.
@en
Alternative splicing of Cav1.2 ...... ectrophysiological properties.
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Alternative splicing of Cav1.2 ...... ectrophysiological properties.
@en
Alternative splicing of Cav1.2 ...... ectrophysiological properties.
@nl
P2093
P2860
P1476
Alternative splicing of Cav1.2 ...... ectrophysiological properties.
@en
P2093
Alejandro M Dopico
Eva Blaskova
Jianxi Liu
Jonathan H Jaggar
Judith Pachuau
Maria Asuncion-Chin
Xiaoyang Cheng
P2860
P304
P356
10.1152/AJPHEART.00109.2009
P577
2009-06-05T00:00:00Z