Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
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Zinc and the modulation of redox homeostasisZn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.Overexpression of Ubiquinol-Cytochrome c Reductase Core Protein 1 May Protect H9c2 Cardiac Cells by Binding with Zinc.Effects of postconditioning with N,N,N'N'-tetrakis-[2-pyridylmethyl]-ethylenediamine in isolated rat hearts.The critical role of intracellular zinc in adenosine A(2) receptor activation induced cardioprotection against reperfusion injuryAldehyde dehydrogenase 2 knockout accentuates ethanol-induced cardiac depression: role of protein phosphatases.Biological consequences of zinc deficiency in the pathomechanisms of selected diseases.Calcium and zinc dyshomeostasis during isoproterenol-induced acute stressor state.Multiple low-dose radiation prevents type 2 diabetes-induced renal damage through attenuation of dyslipidemia and insulin resistance and subsequent renal inflammation and oxidative stress.Intracellular zinc release-activated ERK-dependent GSK-3β-p53 and Noxa-Mcl-1 signaling are both involved in cardiac ischemic-reperfusion injury.Increased reactive oxygen species production during reductive stress: The roles of mitochondrial glutathione and thioredoxin reductases.Danshensu protects isolated heart against ischemia reperfusion injury through activation of Akt/ERK1/2/Nrf2 signaling.Low-dose radiation activates Akt and Nrf2 in the kidney of diabetic mice: a potential mechanism to prevent diabetic nephropathy.Na(+)/Ca(2+) exchanger 1 (NCX-1) mediates the anti-apoptotic effect of Akt1 in neonatal rat cardiomyocytes during ischemia/reperfusion.A mechanism for epithelial-mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3).Renal improvement by zinc in diabetic mice is associated with glucose metabolism signaling mediated by metallothionein and Akt, but not Akt2.Diabetic inhibition of preconditioning- and postconditioning-mediated myocardial protection against ischemia/reperfusion injury.Zinc homeostasis in the metabolic syndrome and diabetes.Epigallocatechin-3-gallate and zinc provide anti-apoptotic protection against hypoxia/reoxygenation injury in H9c2 rat cardiac myoblast cellsCytotoxic effect of ZnS nanoparticles on primary mouse retinal pigment epithelial cells.Phosphorylation of zinc channel ZIP7 drives MAPK, PI3K and mTOR growth and proliferation signalling.Ginsenoside Rb1 protects cardiomyocytes against CoCl2-induced apoptosis in neonatal rats by inhibiting mitochondria permeability transition pore opening.Involvement of glutamatergic neurotransmission in the antidepressant-like effect of zinc in the chronic unpredictable stress model of depression.Zinc oxide nanoparticles harness autophagy to induce cell death in lung epithelial cells.PTEN interacts with metal-responsive transcription factor 1 and stimulates its transcriptional activity.Cardioprotective effect of zinc requires ErbB2 and Akt during hypoxia/reoxygenation.Zinc prevents mitochondrial superoxide generation by inducing mitophagy in the setting of hypoxia/reoxygenation in cardiac cells.Apelin-APJ effects of ginsenoside-Rb1 depending on hypoxia-induced factor 1α in hypoxia neonatal cardiomyocytes.
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Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 12 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
@en
Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
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type
label
Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
@en
Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
@nl
prefLabel
Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
@en
Molecular mechanism underlying Akt activation in zinc-induced cardioprotection.
@nl
P2093
P2860
P1476
Molecular mechanism underlying Akt activation in zinc-induced cardioprotection
@en
P2093
David A Zvara
Rachel McIntosh
Sungryul Lee
Zhelong Xu
P2860
P304
P356
10.1152/AJPHEART.00293.2009
P50
P577
2009-06-12T00:00:00Z