Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines.
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Herbal medicines and nonalcoholic fatty liver diseaseDioscin strengthens the efficiency of adriamycin in MCF-7 and MCF-7/ADR cells through autophagy induction: More than just down-regulation of MDR1.Saponins from Chinese Medicines as Anticancer AgentsGene Expression Profiling associated with Hepatoxicity in Pregnant Rats treated with Ubi Gadong (Dioscorea hispida) ExtractDioscin Induces Gallbladder Cancer Apoptosis by Inhibiting ROS-Mediated PI3K/AKT SignallingInhibition of lung tumor growth by targeting EGFR/VEGFR-Akt/NF-κB pathways with novel theanine derivativesPotent effects of dioscin against liver fibrosis.Matrine-induced autophagy counteracts cell apoptosis via the ERK signaling pathway in osteosarcoma cells.Dioscin alleviates alcoholic liver fibrosis by attenuating hepatic stellate cell activation via the TLR4/MyD88/NF-κB signaling pathwaySteroidal Saponin Diosgenin from Dioscorea bulbifera Protects Cardiac Cells from Hypoxia-reoxygenation Injury Through Modulation of Pro-survival and Pro-death MoleculesDerivatives of 6-cinnamamido-quinoline-4-carboxamide impair lysosome function and induce apoptosis.Polyphyllin G induce apoptosis and autophagy in human nasopharyngeal cancer cells by modulation of AKT and mitogen-activated protein kinase pathways in vitro and in vivo.Potent effects of dioscin against obesity in miceRestoration of autophagy by puerarin in lead-exposed primary rat proximal tubular cells via regulating AMPK-mTOR signaling.Dioscin Protects ANIT-Induced Intrahepatic Cholestasis Through Regulating Transporters, Apoptosis and Oxidative Stress.Synthesis, characterization, and biological studies of diosgenyl analogs.Timosaponin AIII mediates caspase activation and induces apoptosis through JNK1/2 pathway in human promyelocytic leukemia cells.Dioscin induces caspase-independent apoptosis through activation of apoptosis-inducing factor in breast cancer cells.Suppression of autophagy enhances preferential toxicity of paclitaxel to folliculin-deficient renal cancer cellsProtective effects of dioscin against alcohol-induced liver injury.Shikonin promotes autophagy in BXPC-3 human pancreatic cancer cells through the PI3K/Akt signaling pathway.Dioscin Exerts Protective Effects Against Crystalline Silica-induced Pulmonary Fibrosis in Mice.Protective effects of dioscin against cisplatin-induced nephrotoxicity via the microRNA-34a/sirtuin 1 signalling pathway.Dihydrodiosgenin protects against experimental acute pancreatitis and associated lung injury through mitochondrial protection and PI3Kγ/Akt inhibition.Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression.Soluplus/TPGS mixed micelles for dioscin delivery in cancer therapy.Potent effects of dioscin against pancreatic cancer via miR-149-3P-mediated inhibition of the Akt1 signalling pathway.Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.[Advances in the Research of the Regulation of Chinese Traditional Medicine Monomer and Its Derivatives on Autophagy in Non-small Cell Lung Cancer].Dioscin suppresses the viability of ovarian cancer cells by regulating the VEGFR2 and PI3K/AKT/MAPK signaling pathways.
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P2860
Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell lines.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 04 April 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Dioscin-induced autophagy miti ...... human lung cancer cell lines.
@en
Dioscin-induced autophagy miti ...... human lung cancer cell lines.
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type
label
Dioscin-induced autophagy miti ...... human lung cancer cell lines.
@en
Dioscin-induced autophagy miti ...... human lung cancer cell lines.
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prefLabel
Dioscin-induced autophagy miti ...... human lung cancer cell lines.
@en
Dioscin-induced autophagy miti ...... human lung cancer cell lines.
@nl
P2093
P2860
P921
P1476
Dioscin-induced autophagy miti ...... human lung cancer cell lines.
@en
P2093
Chau-Jong Wang
Hui-Ling Chiou
Ming-Ju Hsieh
Te-Lung Tsai
Yih-Shou Hsieh
P2860
P2888
P304
P356
10.1007/S00204-013-1047-Z
P577
2013-04-04T00:00:00Z