Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats.
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Astrocytes differentially respond to inflammatory autoimmune insults and imbalances of neural activity.Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsyRelevance of the glutathione system in temporal lobe epilepsy: evidence in human and experimental modelsRole of astrocytes in epilepsyRoles of glutamine synthetase inhibition in epilepsyEffects of site-specific infusions of methionine sulfoximine on the temporal progression of seizures in a rat model of mesial temporal lobe epilepsy.Seizure-induced oxidative stress in temporal lobe epilepsyPhysiological bases of the K+ and the glutamate/GABA hypotheses of epilepsy.Glutamine acts as a neuroprotectant against DNA damage, beta-amyloid and H2O2-induced stress.The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroencephalographic study.Electrographic seizures are significantly reduced by in vivo inhibition of neuronal uptake of extracellular glutamine in rat hippocampus.Somatotopic astrocytic activity in the somatosensory cortex.A Transient Upregulation of Glutamine Synthetase in the Dentate Gyrus Is Involved in Epileptogenesis Induced by Amygdala Kindling in the Rat.Brain to blood glutamate scavenging as a novel therapeutic modality: a reviewA simple method for measuring intracellular activities of glutamine synthetase and glutaminase in glial cells.Mitochondria, oxidative stress, and temporal lobe epilepsyRosiglitazone Suppresses In Vitro Seizures in Hippocampal Slice by Inhibiting Presynaptic Glutamate Release in a Model of Temporal Lobe EpilepsyAltered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsyAstrocytic regulation of glutamate homeostasis in epilepsyEvidence for astrocytes as a potential source of the glutamate excess in temporal lobe epilepsy.The role of astroglia in the epileptic brain.Blood-brain barrier dysfunction in epileptogenesis of the temporal lobeInhibition of glutamine synthetase in the central nucleus of the amygdala induces anhedonic behavior and recurrent seizures in a rat model of mesial temporal lobe epilepsy.Gene expression of glutamate metabolizing enzymes in the hippocampal formation in human temporal lobe epilepsy.Sleep modifications in acute transient global amnesia.Seizure-like activity in hyaluronidase-treated dissociated hippocampal culturesRegulation of astrocyte glutamine synthetase in epilepsyBlood-brain barrier breakdown-inducing astrocytic transformation: novel targets for the prevention of epilepsy.Astrocyte glutamine synthetase: importance in hyperammonemic syndromes and potential target for therapyNovel astrocyte targets: new avenues for the therapeutic treatment of epilepsyMechanisms of Excessive Extracellular Glutamate Accumulation in Temporal Lobe Epilepsy.Glutamine Synthetase: Role in Neurological Disorders.The Glutamate-Glutamine Cycle in Epilepsy.The conversion of glutamate by glutamine synthase in neocortical astrocytes from juvenile rat is important to limit glutamate spillover and peri/extrasynaptic activation of NMDA receptors.Turning down the volume: Astrocyte volume change in the generation and termination of epileptic seizures.Changes in Hippocampal Volume are Correlated with Cell Loss but Not with Seizure Frequency in Two Chronic Models of Temporal Lobe Epilepsy.Enhanced sensitivity of laforin- and malin-deficient mice to the convulsant agent pentylenetetrazoleeIF2α links mitochondrial dysfunction to dendritic degeneration.Glutamine is required for persistent epileptiform activity in the disinhibited neocortical brain slice.Low plasma antioxidant status in patients with epilepsy and the role of antiepileptic drugs on oxidative stress.
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P2860
Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 July 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Recurrent seizures and brain p ...... se in the hippocampus in rats.
@en
Recurrent seizures and brain p ...... se in the hippocampus in rats.
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type
label
Recurrent seizures and brain p ...... se in the hippocampus in rats.
@en
Recurrent seizures and brain p ...... se in the hippocampus in rats.
@nl
prefLabel
Recurrent seizures and brain p ...... se in the hippocampus in rats.
@en
Recurrent seizures and brain p ...... se in the hippocampus in rats.
@nl
P2093
P2860
P356
P1433
P1476
Recurrent seizures and brain p ...... se in the hippocampus in rats.
@en
P2093
Gauri H Malthankar-Phatak
Henning Beckström
Hitten P Zaveri
James C K Lai
Nihal C de Lanerolle
Tih-Shih W Lee
P2860
P304
P356
10.1093/BRAIN/AWN133
P407
P50
P577
2008-07-06T00:00:00Z