The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts
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From Nutrient to MicroRNA: a Novel Insight into Cell Signaling Involved in Skeletal Muscle Development and DiseaseRTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migrationCSTP1, a novel protein phosphatase, blocks cell cycle, promotes cell apoptosis, and suppresses tumor growth of bladder cancer by directly dephosphorylating Akt at Ser473 site.Reprogramming induced by isoliquiritigenin diminishes melanoma cachexia through mTORC2-AKT-GSK3β signalingThe kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.Frontier of epilepsy research - mTOR signaling pathway.Phospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes.Raptor and Rheb negatively regulate skeletal myogenesis through suppression of insulin receptor substrate 1 (IRS1).Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2.Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.mTOR complex 2 signaling and functionsNegative regulation of initial steps in skeletal myogenesis by mTOR and other kinasesMicroRNA-148a promotes myogenic differentiation by targeting the ROCK1 gene.Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).Mammalian target of rapamycin (mTOR) signaling network in skeletal myogenesis.The role of microRNAs in skeletal muscle health and diseaseHeterogeneous nuclear ribonucleoprotein M associates with mTORC2 and regulates muscle differentiation.Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells in vitro.mTOR and the differentiation of mesenchymal stem cells.The myogenic kinome: protein kinases critical to mammalian skeletal myogenesis.Effects of epidermal growth factor receptor and phosphatase and tensin homologue gene expression on the inhibition of U87MG glioblastoma cell proliferation induced by protein kinase inhibitors.Multispecies-compatible antitumor effects of a cross-species small-interfering RNA against mammalian target of rapamycin.1α,25(OH)2D3-dependent modulation of Akt in proliferating and differentiating C2C12 skeletal muscle cells.O(2) regulates skeletal muscle progenitor differentiation through phosphatidylinositol 3-kinase/AKT signaling.Hepatic CD206-positive macrophages express amphiregulin to promote the immunosuppressive activity of regulatory T cells in HBV infection.mTOR kinase-dependent, but raptor-independent regulation of downstream signaling is important for cell cycle exit and myogenic differentiation.NGF signaling in PC12 cells: the cooperation of p75(NTR) with TrkA is needed for the activation of both mTORC2 and the PI3K signalling cascade.Propofol mediates signal transducer and activator of transcription 3 activation and crosstalk with phosphoinositide 3-kinase/AKT.4,4'-Dichlorodiphenyltrichloroethane (DDT) and 4,4'-dichlorodiphenyldichloroethylene (DDE) inhibit myogenesis in C2C12 myoblasts.MYCN drives glutaminolysis in neuroblastoma and confers sensitivity to an ROS augmenting agent.Effect of 8-week leucine supplementation and resistance exercise training on muscle hypertrophy and satellite cell activation in rats.
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The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 29 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts
@en
The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.
@nl
type
label
The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts
@en
The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.
@nl
prefLabel
The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts
@en
The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.
@nl
P2860
P356
P1476
The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts
@en
P2093
Peter J Houghton
P2860
P304
P356
10.1128/MCB.00764-09
P407
P577
2009-06-29T00:00:00Z