ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis
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The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) familyInteraction of tumor cells with the microenvironmentBone and brain metastasis in lung cancer: recent advances in therapeutic strategiesDissecting Tumor-Stromal Interactions in Breast Cancer Bone MetastasisTargeting Breast Cancer MetastasisTargeting RANKL in metastasisAt the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of boneTargeting tumor-stromal interactions in bone metastasisThe calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells.The metalloproteinase ADAMTS1: a comprehensive review of its role in tumorigenic and metastatic pathways.Tumor cell dormancyMetastatic colonization by circulating tumour cellsWhat Is Breast in the Bone?Cyclin D1 determines estrogen signaling in the mammary gland in vivoAssessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesisCharge-Triggered Membrane Insertion of Matrix Metalloproteinase-7, Supporter of Innate Immunity and TumorsBreast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic changeMatrix metalloproteinases: regulators of the tumor microenvironmentmiR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.RANKL/RANK/MMP-1 molecular triad contributes to the metastatic phenotype of breast and prostate cancer cells in vitroMurine models of breast cancer bone metastasisMalignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer.PGF2α-F-prostanoid receptor signalling via ADAMTS1 modulates epithelial cell invasion and endothelial cell function in endometrial cancer.Metabolomic changes accompanying transformation and acquisition of metastatic potential in a syngeneic mouse mammary tumor modelMolecular mechanisms of bone metastasis and associated muscle weakness.Isolation and identification of a distinct side population cancer cells in the human epidermal squamous cancer cell line A431.Hierarchy of breast cancer cells: key to reverse dormancy for therapeutic intervention.In vivo dynamics and distinct functions of hypoxia in primary tumor growth and organotropic metastasis of breast cancer.EGFR may couple moderate alcohol consumption to increased breast cancer risk.Molecular pathogenesis of bone metastases in breast cancer: Proven and emerging therapeutic targetsMicroRNAs associated with metastatic prostate cancerADAM and ADAMTS family proteins and their role in the colorectal cancer etiopathogenesis.Organ-specific enhancement of metastasis by spontaneous ploidy duplication and cell size enlargement.Decreased autocrine EGFR signaling in metastatic breast cancer cells inhibits tumor growth in bone and mammary fat padMutational profiling of bone metastases from lung adenocarcinoma: results of a prospective study (POUMOS-TEC)EGFR signaling in breast cancer: bad to the bone.Biology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond.Pericellular proteolysis in cancerAn approach for the identification of targets specific to bone metastasis using cancer genes interactome and gene ontology analysis.The role of MMP-1 in breast cancer growth and metastasis to the brain in a xenograft model
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ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 July 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
ADAMTS1 and MMP1 proteolytical ...... ng cascade for bone metastasis
@en
ADAMTS1 and MMP1 proteolytical ...... g cascade for bone metastasis.
@nl
type
label
ADAMTS1 and MMP1 proteolytical ...... ng cascade for bone metastasis
@en
ADAMTS1 and MMP1 proteolytical ...... g cascade for bone metastasis.
@nl
prefLabel
ADAMTS1 and MMP1 proteolytical ...... ng cascade for bone metastasis
@en
ADAMTS1 and MMP1 proteolytical ...... g cascade for bone metastasis.
@nl
P2093
P2860
P356
P1433
P1476
ADAMTS1 and MMP1 proteolytical ...... ng cascade for bone metastasis
@en
P2093
Catherine Van Poznak
Guohong Hu
Joan Massagué
Martin Fleisher
Michael Reiss
Qiongqing Wang
Yibin Kang
P2860
P304
P356
10.1101/GAD.1824809
P577
2009-07-16T00:00:00Z