Discovery of geranylgeranyltransferase-I inhibitors with novel scaffolds by the means of quantitative structure-activity relationship modeling, virtual screening, and experimental validation.
about
Identification and characterization of mechanism of action of P61-E7, a novel phosphine catalysis-based inhibitor of geranylgeranyltransferase-ISoftware and resources for computational medicinal chemistryTargeting protein prenylation for cancer therapyCombined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzymeDiscovery of Natural Product-Derived 5-HT1A Receptor Binders by Cheminfomatics Modeling of Known Binders, High Throughput Screening and Experimental Validation.Statistical analysis, optimization, and prioritization of virtual screening parameters for zinc enzymes including the anthrax toxin lethal factor.Cheminfomatic-based Drug Discovery of Human Tyrosine Kinase Inhibitors.
P2860
Q28477527-57214F07-2B5F-40C1-857F-32B576D95E25Q28728561-4C4CAE5B-290F-46D0-AE06-9DB3930DD980Q33679239-84AC4089-1C65-47AB-9B81-93851C0E5DCAQ35590750-4D7C7508-B4B3-4A0E-805F-5F9B5557825FQ35681838-94781DB9-E7BF-42FC-A04A-C1534C0A3FCBQ36243872-3A6025E4-70DD-4683-9761-5FB9763E2730Q36669662-F33A4416-246B-48DA-AC49-F6D4AD1FEEDD
P2860
Discovery of geranylgeranyltransferase-I inhibitors with novel scaffolds by the means of quantitative structure-activity relationship modeling, virtual screening, and experimental validation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Discovery of geranylgeranyltra ...... , and experimental validation.
@en
Discovery of geranylgeranyltra ...... , and experimental validation.
@nl
type
label
Discovery of geranylgeranyltra ...... , and experimental validation.
@en
Discovery of geranylgeranyltra ...... , and experimental validation.
@nl
prefLabel
Discovery of geranylgeranyltra ...... , and experimental validation.
@en
Discovery of geranylgeranyltra ...... , and experimental validation.
@nl
P2093
P2860
P356
P1476
Discovery of geranylgeranyltra ...... , and experimental validation.
@en
P2093
Patrick J Casey
Xiang S Wang
Yuri K Peterson
P2860
P304
P356
10.1021/JM8013772
P407
P577
2009-07-01T00:00:00Z