Gestational hypoxia induces preeclampsia-like symptoms via heightened endothelin-1 signaling in pregnant rats.
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The placental pursuit for an adequate oxidant balance between the mother and the fetusGestational hypoxia up-regulates protein kinase C and inhibits calcium-activated potassium channels in ovine uterine arteries.Downregulation of microvascular endothelial type B endothelin receptor is a central vascular mechanism in hypertensive pregnancySingle administration of ultra-low-dose lipopolysaccharide in rat early pregnancy induces TLR4 activation in the placenta contributing to preeclampsia.Hypoxia Represses ER-α Expression and Inhibits Estrogen-Induced Regulation of Ca2+-Activated K+ Channel Activity and Myogenic Tone in Ovine Uterine Arteries: Causal Role of DNA MethylationEndothelin-1 and the kidney: new perspectives and recent findings.Placental phenotype and resource allocation to fetal growth are modified by the timing and degree of hypoxia during mouse pregnancy.Up-regulation of CD81 inhibits cytotrophoblast invasion and mediates maternal endothelial cell dysfunction in preeclampsiaThe Endothelin Type A Receptor as a Potential Therapeutic Target in Preeclampsia.Thrombosis during pregnancy: Risks, prevention, and treatment for mother and fetus--harvesting the power of omic technology, biomarkers and in vitro or in vivo models to facilitate the treatment of thrombosis.Understanding Pre-Eclampsia Using Alzheimer's Etiology: An Intriguing Viewpoint.Increased vascular and uteroplacental matrix metalloproteinase-1 and -7 levels and collagen type I deposition in hypertension in pregnancy: role of TNF-α.RhoB/ROCK mediates oxygen-glucose deprivation-stimulated syncytiotrophoblast microparticle shedding in preeclampsia.Role of the endothelin system in sexual dimorphism in cardiovascular and renal diseases.Down-regulated long non-coding RNA MEG3 and its effect on promoting apoptosis and suppressing migration of trophoblast cells.Maternal vascular responses to hypoxia in a rat model of intrauterine growth restriction.Restoring placental growth factor-soluble fms-like tyrosine kinase-1 balance reverses vascular hyper-reactivity and hypertension in pregnancyHypoxia-Induced Activation of JAK/STAT3 Signaling Pathway Promotes Trophoblast Cell Viability and Angiogenesis in PreeclampsiaDown but not out: an emerging role for the B-type endothelin receptor in placental ischemia-induced hypertension.Direct effect of chronic hypoxia in suppressing large conductance Ca(2+)-activated K(+) channel activity in ovine uterine arteries via increasing oxidative stress.MicroRNA-210 Targets Ten-Eleven Translocation Methylcytosine Dioxygenase 1 and Suppresses Pregnancy-Mediated Adaptation of Large Conductance Ca2+-Activated K+ Channel Expression and Function in Ovine Uterine Arteries.Angiogenic imbalance and diminished matrix metalloproteinase-2 and -9 underlie regional decreases in uteroplacental vascularization and feto-placental growth in hypertensive pregnancy.Hypertension and haemodynamics in pregnant women--is a unified theory for pre-eclampsia possible?Decreased homodimerization and increased TIMP-1 complexation of uteroplacental and uterine arterial matrix metalloproteinase-9 during hypertension-in-pregnancy.Curcumin inhibits placental inflammation to ameliorate LPS-induced adverse pregnancy outcomes in mice via upregulation of phosphorylated Akt.The Endothelin System: A Critical Player in the Pathophysiology of Preeclampsia.Placental Growth Factor Reverses Decreased Vascular and Uteroplacental MMP-2 and -9 and increased MMP-1 and -7 and Collagen I and IV in Hypertensive Pregnancy.Near to One's Heart: The Intimate Relationship Between the Placenta and Fetal Heart.
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Gestational hypoxia induces preeclampsia-like symptoms via heightened endothelin-1 signaling in pregnant rats.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Gestational hypoxia induces pr ...... -1 signaling in pregnant rats.
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Gestational hypoxia induces pr ...... -1 signaling in pregnant rats.
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type
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Gestational hypoxia induces pr ...... -1 signaling in pregnant rats.
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Gestational hypoxia induces pr ...... -1 signaling in pregnant rats.
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Gestational hypoxia induces pr ...... -1 signaling in pregnant rats.
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Gestational hypoxia induces pr ...... -1 signaling in pregnant rats.
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P2093
P2860
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P1476
Gestational hypoxia induces pr ...... -1 signaling in pregnant rats.
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Alexandra Paradis
Eugenia Mata-Greenwood
Jianjun Zhou
Lubo Zhang
Zhiqun Wang
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P304
P356
10.1161/HYPERTENSIONAHA.113.01449
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P50
P577
2013-07-01T00:00:00Z