Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
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The novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organizationThe Guanine nucleotide exchange factor kalirin-7 is a novel synphilin-1 interacting protein and modifies synphilin-1 aggregate transport and formationMechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disordersKalirin-7 is required for synaptic structure and functionKalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypesKalirin-7: linking spine plasticity and behaviorControl of Dendritic Spine Morphological and Functional Plasticity by Small GTPasesAbnormal kalirin signaling in neuropsychiatric disorders.Mechanisms for spatiotemporal regulation of Rho-GTPase signaling at synapsesKalirin binds the NR2B subunit of the NMDA receptor, altering its synaptic localization and functionKalrn plays key roles within and outside of the nervous systemScaffold protein X11α interacts with kalirin-7 in dendrites and recruits it to Golgi outpostsBidirectional regulation of synaptic transmission by BRAG1/IQSEC2 and its requirement in long-term depressionRegulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complexNeuronal Actin Dynamics, Spine Density and Neuronal Dendritic Complexity Are Regulated by CAP2Epac2-mediated dendritic spine remodeling: implications for disease.Hippocampal phenotypes in kalirin-deficient mice.Mechanical coupling between transsynaptic N-cadherin adhesions and actin flow stabilizes dendritic spines.Kalirin loss results in cortical morphological alterationsCoordinated nuclear and synaptic shuttling of afadin promotes spine plasticity and histone modificationsOrganization of NMDA receptors at extrasynaptic locations.Kalrn promoter usage and isoform expression respond to chronic cocaine exposureN-cadherin mediates plasticity-induced long-term spine stabilizationBehavioral and morphological responses to cocaine require kalirin7.Kalirin-7, an important component of excitatory synapses, is regulated by estradiol in hippocampal neuronsKalirin-7 is necessary for normal NMDA receptor-dependent synaptic plasticitySynaptic loss and retention of different classic cadherins with LTP-associated synaptic structural remodeling in vivo.p75 regulates Purkinje cell firing by modulating SK channel activity through Rac1.Dendritic spine dynamics--a key role for kalirin-7.Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling.Identification of kalirin-7 as a potential post-synaptic density signaling hubN-cadherin relocalizes from the periphery to the center of the synapse after transient synaptic stimulation in hippocampal neurons.Huntingtin-associated protein 1 interacts with breakpoint cluster region protein to regulate neuronal differentiation.Control of synapse development and plasticity by Rho GTPase regulatory proteins.Afadin, a Ras/Rap effector that controls cadherin function, promotes spine and excitatory synapse density in the hippocampusAbnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia.Rapid estradiol modulation of neuronal connectivity and its implications for disease.Organization of central synapses by adhesion molecules.Actin Out: Regulation of the Synaptic Cytoskeleton.Afadin is required for maintenance of dendritic structure and excitatory tone.
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Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on June 2008
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
@en
Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
@nl
type
label
Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
@en
Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
@nl
prefLabel
Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
@en
Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
@nl
P2093
P2860
P50
P1476
Coordination of synaptic adhesion with dendritic spine remodeling by AF-6 and kalirin-7.
@en
P2093
Cassandra Y Shum
Huzefa Photowala
Kevin M Woolfrey
Richard L Huganir
P2860
P304
P356
10.1523/JNEUROSCI.1170-08.2008
P407
P577
2008-06-01T00:00:00Z