Just say no to ATOH: how HIC1 methylation might predispose medulloblastoma to lineage addiction.
about
The genetics of hair cell development and regenerationCerebellum development and medulloblastomaThe Role of Atonal Factors in Mechanosensory Cell Specification and FunctionThe receptor tyrosine kinase EphA2 is a direct target gene of hypermethylated in cancer 1 (HIC1).Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteinsDeciphering HIC1 control pathways to reveal new avenues in cancer therapeutics.The role of Atonal transcription factors in the development of mechanosensitive cells.Prognostic relevance of high atonal homolog-1 expression in Merkel cell carcinoma.Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas.The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53.Novel gene expression model for outcome prediction in paediatric medulloblastoma.
P2860
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P2860
Just say no to ATOH: how HIC1 methylation might predispose medulloblastoma to lineage addiction.
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2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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Just say no to ATOH: how HIC1 ...... blastoma to lineage addiction.
@en
Just say no to ATOH: how HIC1 ...... blastoma to lineage addiction.
@nl
type
label
Just say no to ATOH: how HIC1 ...... blastoma to lineage addiction.
@en
Just say no to ATOH: how HIC1 ...... blastoma to lineage addiction.
@nl
prefLabel
Just say no to ATOH: how HIC1 ...... blastoma to lineage addiction.
@en
Just say no to ATOH: how HIC1 ...... blastoma to lineage addiction.
@nl
P2860
P1433
P1476
Just say no to ATOH: how HIC1 ...... blastoma to lineage addiction.
@en
P2093
D Neil Watkins
Kimberly J Briggs
P2860
P304
P356
10.1158/0008-5472.CAN-08-1904
P407
P577
2008-11-01T00:00:00Z