Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models.
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Multiple sclerosis, relapses, and the mechanism of action of adrenocorticotropic hormoneThe Non-Obese Diabetic Mouse Strain as a Model to Study CD8(+) T Cell Function in Relapsing and Progressive Multiple SclerosisNovel Insights and Therapeutics in Multiple SclerosisMultiple Sclerosis and T Lymphocytes: An Entangled StoryTargeting S1P receptors in experimental autoimmune encephalomyelitis in mice improves early deficits in locomotor activity and increases ultrasonic vocalisations.PD-L1 is increased in the spinal cord and infiltrating lymphocytes in experimental allergic encephalomyelitisHuman brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosisImmunological and short-term brain volume changes in relapsing forms of multiple sclerosis treated with interferon beta-1a subcutaneously three times weekly: an open-label two-arm trial.The antiepileptic drug valproic acid restores T cell homeostasis and ameliorates pathogenesis of experimental autoimmune encephalomyelitis.MHC class I-restricted myelin epitopes are cross-presented by Tip-DCs that promote determinant spreading to CD8⁺ T cells.The influence of T cell Ig mucin-3 signaling on central nervous system autoimmune disease is determined by the effector function of the pathogenic T cells.Modeling the heterogeneity of multiple sclerosis in animalsB cell-derived IL-15 enhances CD8 T cell cytotoxicity and is increased in multiple sclerosis patients.Postarrest stalling rather than crawling favors CD8(+) over CD4(+) T-cell migration across the blood-brain barrier under flow in vitro.The neurotrophic hepatocyte growth factor attenuates CD8+ cytotoxic T-lymphocyte activityBlocking initial infiltration of pioneer CD8(+) T-cells into the CNS via inhibition of SHP-2 ameliorates experimental autoimmune encephalomyelitis in mice.Immunology in the Clinic Review Series; focus on metabolic diseases: development of islet autoimmune disease in type 2 diabetes patients: potential sequelae of chronic inflammation.Multiple sclerosis: autoimmunity and viruses.Cytotoxic CD8+ T cell ablation enhances the capacity of regulatory T cells to delay viral elimination in Theiler's murine encephalomyelitis.Accumulation and therapeutic modulation of 6-sulfo LacNAc(+) dendritic cells in multiple sclerosisRecognition of a high affinity MHC class I-restricted epitope of myelin oligodendrocyte glycoprotein by CD8⁺ T cells derived from autoantigen-deficient mice.Fingolimod additionally acts as immunomodulator focused on the innate immune system beyond its prominent effects on lymphocyte recirculationThe majority of infiltrating CD8 T lymphocytes in multiple sclerosis lesions is insensitive to enhanced PD-L1 levels on CNS cells.Multiparametric flow cytometric analysis of whole blood reveals changes in minor lymphocyte subpopulations of multiple sclerosis patients.IL-27 plasma level in relapsing remitting multiple sclerosis subjects: The double-faced cytokine.
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P2860
Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 July 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Contribution of CD8 T lymphocy ...... lerosis and its animal models.
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Contribution of CD8 T lymphocy ...... lerosis and its animal models.
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type
label
Contribution of CD8 T lymphocy ...... lerosis and its animal models.
@en
Contribution of CD8 T lymphocy ...... lerosis and its animal models.
@nl
prefLabel
Contribution of CD8 T lymphocy ...... lerosis and its animal models.
@en
Contribution of CD8 T lymphocy ...... lerosis and its animal models.
@nl
P2093
P2860
P50
P921
P1476
Contribution of CD8 T lymphocy ...... clerosis and its animal models
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Lennart T Mars
Nathalie Arbour
Philippe Saikali
Roland S Liblau
P2860
P304
P356
10.1016/J.BBADIS.2010.07.006
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P577
2010-07-15T00:00:00Z