Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1. - Wikidata - awgldk - TriplyDB

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

http://www.wikidata.org/entity/Q37313745

about

SOD1 misplacing and mitochondrial dysfunction in amyotrophic lateral sclerosis pathogenesis Mitochondrial dysfunction in amyotrophic lateral sclerosis - a valid pharmacological target?RNA-targeted Therapeutics for ALS Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis Protease-resistant SOD1 aggregates in amyotrophic lateral sclerosis demonstrated by paraffin-embedded tissue (PET) blot.Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis.Environmental exposure and mitochondrial epigenetics: study design and analytical challenges Effects of Cellular Pathway Disturbances on Misfolded Superoxide Dismutase-1 in Fibroblasts Derived from ALS Patients Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates.Morpholino-mediated SOD1 reduction ameliorates an amyotrophic lateral sclerosis disease phenotype.Immunodetection of outer membrane proteins by flow cytometry of isolated mitochondria.ALS-linked misfolded SOD1 species have divergent impacts on mitochondria.Endogenous macrophage migration inhibitory factor reduces the accumulation and toxicity of misfolded SOD1 in a mouse model of ALS.An emerging role for misfolded wild-type SOD1 in sporadic ALS pathogenesis.The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis.Stem cells for amyotrophic lateral sclerosis modeling and therapy: myth or fact?Current developments in gene therapy for amyotrophic lateral sclerosis.Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?Metabolic Stress and Disorders Related to Alterations in Mitochondrial Fission or Fusion.Misfolded SOD1 is not a primary component of sporadic ALS.Many roads lead to Rome? Multiple modes of Cu,Zn superoxide dismutase destabilization, misfolding and aggregation in amyotrophic lateral sclerosis.Regulation of mitophagy by the ubiquitin pathway in neurodegenerative diseases.Stage-dependent remodeling of projections to motor cortex in ALS mouse model revealed by a new variant retrograde-AAV9

P2860

Q26785352-11D07091-C5A7-45FF-A9B8-B0632D9AABE3 Q27013585-F7CD8669-678C-47AD-98DB-777F91D22B68 Q28083290-64864BDA-5765-455F-9A53-BDDDBF8920C8 Q33819255-355F5791-764C-4515-912A-3706012B22CB Q34143918-486FDC73-1747-4F11-89B8-2707ABB5B684 Q34317439-8D3E9C8B-0C16-4014-8F00-68425A11C89C Q35153934-B0E88668-1488-441B-A6EF-FB2C21509049 Q35937181-812AF5A5-5F6B-4BA4-89DC-73A4214CB5BE Q36543516-6BEAD0C5-A871-4B6D-9804-6F131C8A9297 Q36583270-5E10A1A4-182E-4F94-BE01-CA4C80368B3E Q36788242-10846B87-2C6D-4C1D-AB6C-5E229A79BC7E Q36842266-1429334B-8F84-4978-A923-646DA2EAA84B Q37247621-8FFC22E6-4078-4801-AA83-21449C0D0C33 Q38174873-83FE3082-94D1-453E-9205-0AFC55DAA20B Q38218666-5EF234EF-3D4D-4595-9027-EA21C3BD0641 Q38341972-38812F80-4EE7-46FF-803A-B491B73CC116 Q38470242-791491D3-33B3-4BAE-BDEF-6B437A55DE12 Q39149919-085ABBCD-0EC3-48E1-8B92-AFF7B73B7E0E Q41949133-54666743-B805-40D9-AA3E-6707FF84EBDC Q45958184-BA3E4F2E-7EBA-47D4-B9C1-0194C807C893 Q46851121-B5F697A0-72D9-4EE3-BCA8-1E50262F6BA5 Q47216699-A7FA7D16-48BF-4270-B462-5F68F9850567 Q58711830-0D5A7745-390A-4E7E-AE6A-3E83EB1E2298

P2860

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

http://www.wikidata.org/entity/Q37313745

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 04 June 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

@en

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

@nl

type

label

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

@en

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

@nl

prefLabel

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

@en

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

@nl

P1433

Q37313745-D5FD9971-49BE-4340-A3EF-4181B44D6690

P1476

Q37313745-E4B7EDA6-B2B7-495A-A387-E29CBC008B15

P2093

Q37313745-09713513-109F-42CA-AE8B-5C8B79C65277

Q37313745-30091BD5-5038-4FDA-A8A4-7500AB6B1B25

Q37313745-C425E0BC-D712-4258-B315-3729DA8704CF

Q37313745-CE5396DE-2F66-455B-B5B8-6194D63F6636

Q37313745-E377297C-47F2-4531-A915-638E5FEE586A

P2860

Q37313745-0B8A47D6-07C9-4B5B-8665-1B519630A72E

Q37313745-1706FFFA-6115-4ECD-B733-A5BF9130577B

Q37313745-29B912B2-0096-4841-9510-929424EB71AF

Q37313745-2C2EC056-A391-4148-AE6B-DE54E09641A9

Q37313745-336DB6CD-C05B-45D4-919F-FDF5D3CDEB9F

Q37313745-374505D1-D81F-4A8F-8E95-F359D2D486A8

Q37313745-38FB0075-31E9-476D-9E93-F01F090CF4CB

Q37313745-39ED3893-FF16-4D85-8047-D6D1737BEC10

Q37313745-3D19A2AC-E302-4253-B216-3D3D940EA3D4

Q37313745-43AFCB3E-1085-499E-8F6B-75BEB2F9511B

P304

Q37313745-0B25E76C-6F04-4C8E-BFEA-DC5DF212403A

P31

Q37313745-5159F6AB-3475-4D8C-B883-8F3D90642F90

P356

Q37313745-C980989C-D1F9-47F9-8E00-C5D8E870985A

P433

Q37313745-26AB31DA-A04F-4429-AD3F-11A4C7AB6ABE

P478

Q37313745-CD6E8385-2FB9-4038-81E1-229BA1120985

P50

Q37313745-0E393751-5318-4E7B-B8DF-A2347C57EDA8

Q37313745-30C46B83-8B1D-45F0-9BD9-357D5473ADEB

Q37313745-D2F9D65E-4661-4C23-BA5B-327C68ADA992

Q37313745-DB816AC5-3E63-471F-8746-71B8DB60FA8F

P577

Q37313745-255D7C94-A557-4E72-B2C0-B96DE6680219

P5875

Q37313745-EA963CA5-9F6C-4D92-B864-0AEBEED3D555

P698

Q37313745-E98363CA-E3C0-4AF0-B7A3-3243DCAFC116

P921

Q37313745-8C219F3D-F565-4A83-A54E-11B789460C54

Q37313745-9945F970-BECB-4FAB-BEEA-0D499930405C

P932

Q37313745-6AEA0E85-AAC0-45A6-BA31-3A9D7C2D8CDA

P356

P1433

Human Molecular Genetics

P1476

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1.

@en

P2093

Christine Vande Velde

http://www.w3.org/2001/XMLSchema#string

Jean-Pierre Julien

http://www.w3.org/2001/XMLSchema#string

Sarah Cadot

http://www.w3.org/2001/XMLSchema#string

Sarah L Peyrard

http://www.w3.org/2001/XMLSchema#string

Sarah Pickles

http://www.w3.org/2001/XMLSchema#string

P2860

ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes

Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria

MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models

Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS

ALS: a disease of motor neurons and their nonneuronal neighbors

Onset and progression in inherited ALS determined by motor neurons and microglia

Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.

Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form.

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS.

Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons.

P304

3947-3959

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/HMG/DDT249

http://www.w3.org/2001/XMLSchema#string

P433

19

http://www.w3.org/2001/XMLSchema#string

P478

22

http://www.w3.org/2001/XMLSchema#string

P50

Laurie Destroismaisons

Nathalie Arbour

P577

2013-06-04T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

237056370

http://www.w3.org/2001/XMLSchema#string

P698

23736301

http://www.w3.org/2001/XMLSchema#string

P921

amyotrophic lateral sclerosis

P932

5052069

http://www.w3.org/2001/XMLSchema#string