Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: a consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase
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Mitochondria Retrograde Signaling and the UPR mt: Where Are We in Mammals?Xenobiotic perturbation of ER stress and the unfolded protein responseUbiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitinationHepatic heme-regulated inhibitor (HRI) eukaryotic initiation factor 2alpha kinase: a protagonist of heme-mediated translational control of CYP2B enzymes and a modulator of basal endoplasmic reticulum stress toneKetamine attenuates cytochrome p450 aromatase gene expression and estradiol-17β levels in zebrafish early life stagesLiver cytochrome P450 3A ubiquitination in vivo by gp78/autocrine motility factor receptor and C terminus of Hsp70-interacting protein (CHIP) E3 ubiquitin ligases: physiological and pharmacological relevance.Liver cytochrome P450 3A endoplasmic reticulum-associated degradation: a major role for the p97 AAA ATPase in cytochrome P450 3A extraction into the cytosol.Impact of ER protein homeostasis on metabolism.Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liverMechanisms of ketamine-involved regulation of cytochrome P450 gene expression.Fenretinide induces ubiquitin-dependent proteasomal degradation of stearoyl-CoA desaturase in human retinal pigment epithelial cells.The comparative effects of diethyldithiocarbamate-copper complex with established proteasome inhibitors on expression levels of CYP1A2/3A4 and their master regulators, aryl hydrocarbon and pregnane X receptor in primary cultures of human hepatocytesGCN2 kinase is a key regulator of fibrogenesis and acute and chronic liver injury induced by carbon tetrachloride in mice.
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Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: a consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 11 June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Hepatic CYP3A suppression by h ...... ctor 2alpha (eIF2alpha)-kinase
@en
Hepatic CYP3A suppression by h ...... ctor 2alpha (eIF2alpha)-kinase
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type
label
Hepatic CYP3A suppression by h ...... ctor 2alpha (eIF2alpha)-kinase
@en
Hepatic CYP3A suppression by h ...... ctor 2alpha (eIF2alpha)-kinase
@nl
prefLabel
Hepatic CYP3A suppression by h ...... ctor 2alpha (eIF2alpha)-kinase
@en
Hepatic CYP3A suppression by h ...... ctor 2alpha (eIF2alpha)-kinase
@nl
P2093
P2860
P356
P1476
Hepatic CYP3A suppression by h ...... ctor 2alpha (eIF2alpha)-kinase
@en
P2093
Juan C Engel
Maria Almira Correia
Poulomi Acharya
P2860
P304
P356
10.1124/MOL.109.056002
P577
2009-06-11T00:00:00Z