Identification of the copper(II) coordinating residues in the prion protein by metal-catalyzed oxidation mass spectrometry: evidence for multiple isomers at low copper(II) loadings
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Copper binding extrinsic to the octarepeat region in the prion proteinCalorimetric investigation of copper binding in the N-terminal region of the prion protein at low copper loading: evidence for an entropically favorable first binding event.Increased protein structural resolution from diethylpyrocarbonate-based covalent labeling and mass spectrometric detectionModeling by assembly and molecular dynamics simulations of the low Cu2+ occupancy form of the mammalian prion protein octarepeat region: gaining insight into Cu2+-mediated beta-cleavage.Correct identification of oxidized histidine residues using electron-transfer dissociation.Copper binding to beta-2-microglobulin and its pre-amyloid oligomers.Unique effect of Cu(II) in the metal-induced amyloid formation of β-2-microglobulinHistidine availability is decisive in ROS-mediated cytotoxicity of copper complexes of Aβ1-16 peptide.The Rich Electrochemistry and Redox Reactions of the Copper Sites in the Cellular Prion Protein.A potential mechanism for Cu2+ reduction, beta-cleavage, and beta-sheet initiation within the N-terminal domain of the prion protein: insights from density functional theory and molecular dynamics calculations.The effect of a membrane-mimicking environment on the interactions of Cu2+ with an amyloidogenic fragment of chicken prion protein.Covalent labeling-mass spectrometry with non-specific reagents for studying protein structure and interactions
P2860
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P2860
Identification of the copper(II) coordinating residues in the prion protein by metal-catalyzed oxidation mass spectrometry: evidence for multiple isomers at low copper(II) loadings
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 August 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Identification of the copper
@nl
Identification of the copper(I ...... ers at low copper(II) loadings
@en
type
label
Identification of the copper
@nl
Identification of the copper(I ...... ers at low copper(II) loadings
@en
prefLabel
Identification of the copper
@nl
Identification of the copper(I ...... ers at low copper(II) loadings
@en
P2093
P2860
P356
P1433
P1476
Identification of the copper(I ...... ers at low copper(II) loadings
@en
P2093
Colin S Burns
Jonathan Wilson
Rapole Srikanth
Richard W Vachet
P2860
P304
P356
10.1021/BI800970M
P407
P577
2008-08-09T00:00:00Z