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Identification of driver genes in hepatocellular carcinoma by exome sequencing.

Identification of driver genes in hepatocellular carcinoma by exome sequencing.

http://www.wikidata.org/entity/Q37315447

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Molecular pathogenesis of hepatocellular carcinoma and impact of therapeutic advances Molecularly targeted therapy for advanced hepatocellular carcinoma - a drug development crisis?The mutational landscape of hepatocellular carcinoma Targeting the mTOR pathway in hepatocellular carcinoma: current state and future trends Epigenetics in liver disease Multidisciplinary perspective of hepatocellular carcinoma: A Pacific Northwest experience.Genetic alterations in hepatocellular carcinoma: An update Epigenetics in liver disease: from biology to therapeutics Dysregulation of ubiquitin ligases in cancer p62 links autophagy and Nrf2 signaling A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells Mutations acquired by hepatocellular carcinoma recurrence give rise to an aggressive phenotype.CRISPR/Cas9-mediated p53 and Pten dual mutation accelerates hepatocarcinogenesis in adult hepatitis B virus transgenic mice.Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors Identification and analysis of driver missense mutations using rotation forest with feature selection.The genomic landscape of fibrolamellar hepatocellular carcinoma: whole genome sequencing of ten patients.Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis.MicroRNAs in liver cancer: a model for investigating pathogenesis and novel therapeutic approaches.Profiling of exome mutations associated with progression of HBV-related hepatocellular carcinoma.Reciprocal interaction of Wnt and RXR-α pathways in hepatocyte development and hepatocellular carcinoma.p53 requires the stress sensor USF1 to direct appropriate cell fate decision.DNA markers in molecular diagnostics for hepatocellular carcinoma.Liver cancer oncogenomics: opportunities and dilemmas for clinical applications.Significance of genetic variants in DLC1 and their association with hepatocellular carcinoma Accumulation of Deleterious Passenger Mutations Is Associated with the Progression of Hepatocellular Carcinoma How do persistent infections with hepatitis C virus cause liver cancer?Epigenomic annotation of noncoding mutations identifies mutated pathways in primary liver cancer Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib.Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma.A genomic case study of mixed fibrolamellar hepatocellular carcinoma Sorafenib in advanced hepatocellular carcinoma: current status and future perspectives.Detecting Circulating Tumor DNA in Hepatocellular Carcinoma Patients Using Droplet Digital PCR Is Feasible and Reflects Intratumoral Heterogeneity The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers.Clinical implication of Keap1 and phosphorylated Nrf2 expression in hepatocellular carcinoma.Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma.From Clinical Standards to Translating Next-Generation Sequencing Research into Patient Care Improvement for Hepatobiliary and Pancreatic Cancers Clinical outcomes based on multigene profiling in metastatic breast cancer patients The importance of a multidisciplinary approach to hepatocellular carcinoma.TP53 and RET may serve as biomarkers of prognostic evaluation and targeted therapy in hepatocellular carcinoma.Examining the impact of gene variants on histone lysine methylation

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Identification of driver genes in hepatocellular carcinoma by exome sequencing.

http://www.wikidata.org/entity/Q37315447

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 24 September 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Identification of driver genes in hepatocellular carcinoma by exome sequencing.

@en

Identification of driver genes in hepatocellular carcinoma by exome sequencing.

@nl

type

label

Identification of driver genes in hepatocellular carcinoma by exome sequencing.

@en

Identification of driver genes in hepatocellular carcinoma by exome sequencing.

@nl

altLabel

Identification of driver genes in hepatocellular carcinoma by exome sequencing

@en

prefLabel

Identification of driver genes in hepatocellular carcinoma by exome sequencing.

@en

Identification of driver genes in hepatocellular carcinoma by exome sequencing.

@nl

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Identification of driver genes in hepatocellular carcinoma by exome sequencing.

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Anand Ghanekar

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Derek Y Chiang

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Gleb L Savich

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Hyeja Kim

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Jinyu Li

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Joel S Parker

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Kui Chen

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Maha Guindi

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Michael C Wu

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Michael S Lawrence

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COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma

Initial genome sequencing and analysis of multiple myeloma

Somatic mutations affect key pathways in lung adenocarcinoma

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Fast gapped-read alignment with Bowtie 2

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

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1693-1702

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scholarly article

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10.1002/HEP.26540

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5

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237005025

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23728943

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3830584

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