Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR family
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Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathwaysSH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complexWhere now for anti-EGF receptor therapies in colorectal cancer?CXCL12 and [N33A]CXCL12 in 5637 and HeLa cells: regulating HER1 phosphorylation via calmodulin/calcineurin.Lipocalin 2 is essential for chronic kidney disease progression in mice and humans.Bisphosphonates inactivate human EGFRs to exert antitumor actions.Occludin is regulated by epidermal growth factor receptor activation in brain endothelial cells and brains of mice with acute liver failure.Muscarinic receptor agonists stimulate human colon cancer cell migration and invasion.Urothelial carcinomas: a focus on human epidermal receptors signalingImpact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation.The role of c-Src in the invasion and metastasis of hepatocellular carcinoma cells induced by association of cell surface GRP78 with activated α2MStructure of the EGF receptor transactivation circuit integrates multiple signals with cell context.Epidermal growth factor receptor protein overexpression and gene amplification are associated with aggressive biological behaviors of esophageal squamous cell carcinomaSarcosine induces increase in HER2/neu expression in androgen-dependent prostate cancer cells.Adaptive Immune Responses and HER2/neu Positive Breast Cancer.Gene amplification of EGFR, HER2, FGFR2 and MET in esophageal squamous cell carcinoma.Huntingtin-interacting protein 1 phosphorylation by receptor tyrosine kinases.A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis.Predictive value of EGFR overexpression and gene amplification on icotinib efficacy in patients with advanced esophageal squamous cell carcinoma.Many cytokines are very useful therapeutic targets in disease.The epidermal growth factor receptor: a link between inflammation and liver cancer.Anti-epidermal growth factor receptor monoclonal antibodies in cancer therapy.Anti-HER agents in gastric cancer: from bench to bedside.Lung cancer and Toll-like receptors.Epidermal growth factor receptor (EGFR) as a therapeutic target in rheumatoid arthritis.Optimizing treatment of metastatic colorectal cancer patients with anti-EGFR antibodies: overcoming the mechanisms of cancer cell resistance.Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer.Therapeutic targeting of hyaluronan in the tumor stroma.Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development.The EGFR/miR-338-3p/EYA2 axis controls breast tumor growth and lung metastasis.Simultaneous β1 integrin-EGFR targeting and radiosensitization of human head and neck cancer.Epidermal growth factor receptor expression in acute myelogenous leukaemia is associated with clinical prognosis.Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12.Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade.HER3 intracellular domains play a crucial role in HER3/HER2 dimerization and activation of downstream signaling pathways.Targeted Therapies Against Growth Factor Signaling in Breast Cancer.Leveraging Genomics for Head and Neck Cancer Treatment.Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines.Synergistic Targeting HER2 and EGFR with Bivalent Aptamer-siRNA Chimera Efficiently Inhibits HER2-Positive Tumor Growth
P2860
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P2860
Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR family
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Signal integration: a framewor ...... argeting the human EGFR family
@en
Signal integration: a framewor ...... rgeting the human EGFR family.
@nl
type
label
Signal integration: a framewor ...... argeting the human EGFR family
@en
Signal integration: a framewor ...... rgeting the human EGFR family.
@nl
prefLabel
Signal integration: a framewor ...... argeting the human EGFR family
@en
Signal integration: a framewor ...... rgeting the human EGFR family.
@nl
P2093
P2860
P356
P1476
Signal integration: a framewor ...... argeting the human EGFR family
@en
P2093
Cathleen M Brdlik
H Michael Shepard
Hans Schreiber
P2860
P304
P356
10.1172/JCI36049
P407
P577
2008-11-01T00:00:00Z